Immune system activity in rheumatic patients

Authors

Keywords:

rheumatic disease, immunosuppression, immunosuppressants, immune system.

Abstract

Rheumatic diseases are a group of conditions, most of them with immunological affectation and systemic compromise, which generate different degrees of functional disability and decrease in the perception of quality of life of the patients who suffer from them. They constitute one of the main causes of disability, of temporary and definitive invalidity, of labor affectation and are among the first 10 reasons for consultations in the first level of health care. Patients with this type of disease have been considered immunocompromised, which does not correspond directly to the mechanisms of production of the vast majority of rheumatic diseases. This report addresses the myths and realities that encompass rheumatic diseases and the supposed immunosuppression they generate, from the etiopathogenic perspective of this group of diseases. The clarification of these elements is essential to be able to deal adequately, from the therapeutic and self-care point of view, with patients with rheumatic diseases. It is concluded that, based on the etiopathogenic elements of rheumatic diseases and the analysis of the expression of the normal immune response and in rheumatic patients, these cannot be considered as immunosuppressed people. The prescription of immunosuppressants is made in order to restore the normal immune response.

Downloads

Download data is not yet available.

Author Biographies

Urbano Solis Cartas, Universidad Nacional de Chimborazo Escuela Superior politécnica de Chimborazo Hospital Andino de Chimborazo

Especialista en Reumatología

Jorge Luis Valdés González, Escuela Superior Politécnica de Chimborazo

Especialista en Dermatología

References

1. Neri Vela R, Lievano Madrigal L. Páginas en la historia de la reumatología en México. Rev. Fac. Med. (Méx.). 2017 [acceso: 01/04/2022]; 60(1): 30-7. Disponible en: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0026-17422017000100030&lng=es

2. Reyes-Llerena G. El arte, la pintura y la reumatología a través de la historia: apuntes y consideraciones reflexivas de un reumatólogo cubano. Revista Cubana de Reumatología. 2021 [acceso: 01/04/2022]; 23(3): e247. Disponible en: http://www.revreumatologia.sld.cu/index.php/reumatologia/article/view/932

3. Iglesias-Gamarra A, Quintana G, Restrepo Suárez JF. Prehistoria, historia y arte de la Reumatología Gota y espondilitis anquilosante. Rev. Colomb. Reumatol. 2006 [acceso: 31/03/2022]; 13(2):120-41. Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0121-81232006000200003&lng=en

4. Cando Ger AE, Valencia Catacta EE, Segovia Torres GA, Tutillo León JA, Paucar Tipantuña LE, Zambrano Carrión MC. Avances en la atención de salud a los pacientes con enfermedades reumáticas. Rev Cuba Reumatol. 2018 [acceso: 02/04/2022]; 20(3): e43. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1817-59962018000300004&lng=es

5. Castillo Fiallos EP, Castillo Vera LJ, Chirao Cudco KE, Parra Cazar TH. Relación entre enfermedades reumáticas y diabetes mellitus. Rev Cuba Reumatol. 2019 [acceso: 30/03/2022]; 21(3): e97. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1817-59962019000300002&lng=es

6. Chapalbay Parreño IC, Ayala Reinoso P, Campos Ruiz LF, Orna Brito VH, Martínez Larrarte JP. Adherencia farmacológica en pacientes con enfermedades reumáticas. Rev Cuba Reumatol. 2019 [acceso: 01/04/2022]; 21(3):e99. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1817-59962019000300003&lng=es

7. Solis Cartas U, Calvopiña Bejarano SJ, Nuñez Sánchez BL, Yartú Couceiro R. Relación entre adiposidad corporal y presión arterial en niños y adolescentes con enfermedades reumáticas. Rev Cuba Reumatol. 2019 [acceso: 29/03/2022]; 21(1):e51. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1817-59962019000100002&lng=es

8. Iglesias D, Castro Iglesias M, Torres Pérez L. COVID-19, aterosclerosis y la respuesta inflamatoria en la enfermedad reumática. Rev cubana med. 2021 [acceso: 29/03/2022]; 60(4):e2588. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75232021000400018&lng=es

9. Mejía Navarro AA, Mejía Navarro JC, Tenorio Correa SM. Usefulness of the determination of antibodies in the diagnosis of rheumatic diseases. Rev Cuba Reumatol. 2019 [acceso: 01/04/2022]; 21(2):e83. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1817-59962019000200012&lng=es

10. Cazar-Chávez M, Pino-Falconí P, Moya-Romero K, Muñiz-Vásquez V. Nuevo panorama para las enfermedades reumáticas pediátricas. Revista Cubana de Reumatología. 2021 [acceso: 02/04/2022]; 24(2):e264. Disponible en: http://www.revreumatologia.sld.cu/index.php/reumatologia/article/view/980

11. González Maestrey A, García Menéndez G, Rangel Velázquez S, Pérez Gómez D. Necesidades de capacitación para el diagnóstico genético de espondiloartropatías en médicos del Hospital “Hermanos Ameijeiras”. EDUMECENTRO. 2019 [acceso: 02/04/2022]; 11(3):104-15. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S2077-28742019000300104&lng=es

12. Solis Cartas U, Morejón Gómez JA, de Armas Hernández A. Ankylosing Spondylitis and Illness of Von Recklinhausen. An uncommon association. Rev Cuba Reumatol. 2014 [acceso: 31/03/2022]; 16(2):240-4. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1817-59962014000200010&lng=es

13. Scublinsky D, Pinoni MV, Ibelli F, Valledor A, Soriano ER. Formas clínicas y diagnóstico de la enfermedad de Chagas e inmunosupresores. Rev. argent. reumatolg. 2019 [acceso: 01/04/2022]; 30(1):11-4. Disponible en: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S2362-36752019000100003&lng=es

14. Cortés Jorge A. Anergia e inmunosupresión en pacientes con artritis reumatoide. Rev. Colomb. Reumatol. 2021 [acceso: 30/03/2022]; 28(1):1-3. Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0121-81232021000100001&lng=en

15. Sánchez-Salguero ES, Santos-Argumedo L. La asociación de la microbiota humana con la inmunoglobulina A y su participación en la respuesta inmunológica. Rev. alerg. Méx. 2018 [acceso: 01/04/2022]; 65(3):264-78. Disponible en: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S2448-91902018000300184&lng=es

Downloads

Published

2022-07-28

How to Cite

1.
Solis Cartas U, Valdés González JL. Immune system activity in rheumatic patients. Rev Cubana Med Milit [Internet]. 2022 Jul. 28 [cited 2025 Jul. 1];51(4):e02202029. Available from: https://revmedmilitar.sld.cu/index.php/mil/article/view/2029

Issue

Vol. 51 No. 4 (2022): October - December

Section

Opinion Article

License

Authors who have publications with this Journal accept the following terms:

  • The authors will retain their copyright and guarantee the Journal the right of first publication of their work, which will simultaneously be subject to the Creative Commons Attribution License. The content presented here can be shared, copied and redistributed in any medium or format; Can be adapted, remixed, transformed or created from the material, using the following terms: Attribution (giving appropriate credit to the work, providing a link to the license, and indicating if changes have been made); non-commercial (you cannot use the material for commercial purposes) and share-alike (if you remix, transform or create new material from this work, you can distribute your contribution as long as you use the same license as the original work).
  • The authors may adopt other non-exclusive license agreements for the distribution of the published version of the work (for example: depositing it in an institutional electronic archive or publishing it in a monographic volume) as long as the initial publication in this Journal is indicated.
  • Authors are allowed and recommended to disseminate their work through the Internet (e.g., in institutional electronic archives or on their website) before and during the submission process, which can produce interesting exchanges and increase citations. of the published work.