Current considerations of percutaneous ethanol injection in benign nodular goiter

Authors

Keywords:

nodular goiter, ethanol, therapeutics.

Abstract

Introduction: Percutaneous ethanol injection has been used in the treatment of small hepatocellular carcinomas, metastatic liver lesions, primary or secondary parathyroid adenomas, and, sporadically, other benign endocrine neoplasms such as aldosterone-producing adrenocortical adenomas.
Objectives: To update the knowledge of the current use and the results of the percutaneous injection of ethanol for the treatment of patients with nodular goiter.
Development: Current evidence supports the use of percutaneous ethanol injection as first-line treatment for pure cysts and predominantly cystic thyroid nodules. Significantly reduces the volume and the largest diameter in both solid and cystic nodules. In a completely cystic nodule, ethanol ablation can achieve 85% to 95% volume reduction. However, in a predominantly cystic nodule, the rate of volume reduction varies from 60% to 90%. The results for predominantly cystic nodules with a solid portion of less than 20% are satisfactory. In solid thyroid nodules, success rates of 75 to 86.6% are reported, considering the patients who report post-treatment aesthetic improvement.
Conclusions: Percutaneous ethanol injection is used as a safe and effective treatment method for patients with benign nodular goiter. It can be offered as a therapeutic alternative in countries where surgery and clinical observation are the main treatment options for these patients.

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Published

2023-08-21

How to Cite

1.
Lorda Galiano L, Navas Igarza JO, Ortega de la Campa B. Current considerations of percutaneous ethanol injection in benign nodular goiter. Rev Cubana Med Milit [Internet]. 2023 Aug. 21 [cited 2025 Mar. 13];52(3):e02302930. Available from: https://revmedmilitar.sld.cu/index.php/mil/article/view/2930

Issue

Vol. 52 No. 3 (2023): July - september

Section

Review Article

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