Late complications caused by silicone oil in patients vitrectomized for rhegmatogenous retinal detachment
Keywords:
macula lutea, retinal detachment, silicone oils, vitrectomyAbstract
Introduction: Silicone oil is used in patients vitrectomized for rhegmatogenous retinal detachment, early removal is recommended because its permanence may induce complications.
Objective: To describe late complications caused by silicone oil in patients vitrectomized for rhegmatogenous retinal detachment.
Methods: 24 patients were evaluated in a cross-sectional study. Visual acuity without correction at the time of consultation, density of silicone oil and its permanence time in the vitreous cavity, type of late complication, horizontal and vertical macular thickness were evaluated.
Results: Male were predominant (65%), whites (83%), and the age group 50 - 69 years represented 67% of the patients. Fifty-seven percent had no ocular pathological history, 26% presented myopia (13% with high myopia). Thirty-eight percent had visual acuity between 0.1 - 0.3. Silicone oil 100 cSt was used in 83% of the cases and the time of permanence was 23 ± 17 months. Late complications, cataract, ocular hypertension and emulsified oil in equal proportion, macular edema and macular hole occurred in 71% of patients. The average macular thicknesses in horizontal and vertical slices were 478 ± 219 µm and 487 ± 214 µm.
Conclusions: Silicone oil cause macular thickness increase and inflammation mediated visual acuity decrease. Late complications of pars plana vitrectomy in patients with rhegmatogenous retinal detachment, with silicone oil are cataracts, ocular hypertension and emulsified oil.
Downloads
References
1. Claramunt LJ. Desprendimiento de retina [Internet]. Revista Médica Clínica Las Condes. 2010; 21(6):956-60. DOI: https://doi.org/10.1016/S0716-8640(10)70621-0
2. Freire G, Vallejo GEE, Bosquez KMV. Actualización sobre patogenia, clínica y diagnóstico del desprendimiento de retina [Internet]. JAH. 2020 [acceso: 25/09/2024]; 3(2): 117–28. Disponible en: https://www.jah-journal.com/index.php/jah/article/view/39
3. American Academy of Ophthalmology. Posterior Vitreous Detachment, Retinal Breaks, and Lattice Degeneration 019 [Internet]. American Academy of Ophthalmology; 2019. [acceso: 25/09/2024]. Disponible en: https://www.aao.org/education/preferred-practice-pattern/posterior-vitreous-detachment-retinal-breaks-latti
4. Lapido Polanco SI, Dovalina Rivera G, Baldoquín Rodríguez W, Hernández Martínez R, Rodríguez Rodríguez B, Chiang Rodríguez C. Epidemiología del desprendimiento de la retina regmatógeno [Internet]. Revista Cubana de Oftalmología. 2020 [acceso: 25/09/2024]; 33(2): e840 Disponible en: https://revoftalmologia.sld.cu/index.php/oftalmologia/article/view/840/pdf_56
5. Arteaga, DKZ. Manejo del Desprendimiento de Retina Regmatogeno [Internet]. Revista Médica-Científica CAMbios HECAM. 2022; 21(1): 1-10. DOI: 10.36015
6. Schwartz SG, Flynn Jr HW. Pars plana vitrectomy for primary rhegmatogenous retinal detachment [Internet]. Clinical ophthalmology. 2008 [acceso: 05/06/2025]; 2(1):57-63. Disponible en: https://www.tandfonline.com/doi/full/10.2147/opth.s1511
7. Ishikawa K, Hishatomi T, Sakamoto T. Special Adjunts to Treatment. En: Sadda SR editor jefe). Ryan's Retina E-Book [Internet]. New York: Elsevier Health Sciences; 2022. [acceso: 25/09/2024] p. 2092-2142. Disponible en: https://books.google.com.cu/books?hl=es&lr=&id=6H9qEAAAQBAJ&oi=fnd&pg=PP1&dq=Ryan%E2%80%99s.+Retina.+7ma+ed.+London:+New+York+Elsevier%3B+2023&ots=TXxNLQehMP&sig=AEPzL9OnzhzRSxXcl2UI4ddR3nA&redir_esc=y#v=onepage&q&f=false
8. Lu Y, Chan K, Lau H, Wong D, Wong W, Shih KC. Amphiphilic additives in silicone oil tamponade and emulsification: an eye-on-a-chip study [Internet]. Acta Ophthalmol. 2020; 98(2): e232–7. DOI: http://dx.doi.org/10.1111/aos.14212
9. Wolf S, Zinkernagel M. Pathogenic Mechanism of Retinal Detachment. En: Sadda R (editor jefe). Ryan’s. Retina E-Book [Internet]. New York: Elsevier Health Sciences; 2023. [acceso: 25/09/2024]; p. 1941-1947. Disponible en: https://books.google.com.cu/books?hl=es&lr=&id=6H9qEAAAQBAJ&oi=fnd&pg=PP1&dq=Ryan%E2%80%99s.+Retina.+7ma+ed.+London:+New+York+Elsevier%3B+2023&ots=TXxNLQehMP&sig=AEPzL9OnzhzRSxXcl2UI4ddR3nA&redir_esc=y#v=onepage&q&f=false
10. Morales V, Di Luciano A, Adaniya A, Alvarado R, Velickovich D, Roca JA. Complicaciones asociadas al uso de aceite de silicona: revisión sistemática [Internet]. Rev Mex Oftalmol. 2021; 95(2): 76–83.Disponible en: http://dx.doi.org/10.24875/RMO.M20000144
11. Anaya EJ, Sáenz CH, Baeza JA y Rodríguez V. Estudio retrospectivo de complicaciones asociadas al aceite de silicona. Experiencia de 5 años en un hospital público del norte de México [Internet]. Rev Mex Oftalmol. 2017; 91(2): 76–81. DOI: http://dx.doi.org/10.1016/j.mexoft.2016.01.007
12. Marti M, Walton R, Böni C, Zweifel SA, Stahel M, Barthelmes D. Increased intraocular pressure is a risk factor for unexplained visual loss during silicone oil endotamponade [Internet]. Retina. 2017; 37(12): 2334–40. DOI: http://dx.doi.org/10.1097/IAE.0000000000001492
13. Rabina G, Azem N, Barequet D, Barak A, Loewenstein A, Schwartz S. Silicone oil tamponade effect on macular layer thickness and visual acuity [Internet]. Retina. 2020; 40(5): 998–1004. DOI: http://dx.doi.org/10.1097/IAE.0000000000002464
14. Lee J, Cho H, Kang M, Hong R, Seong M, Shin Y. Cambios en la retina antes y después de la eliminación del aceite de silicona en ojos con desprendimiento de retina regmatógeno mediante tomografía de coherencia óptica de fuente de barrido [Internet]. J Clin Med. 2021; 10(22): 5436. DOI: http://dx.doi.org/10.3390/jcm10225436
15. Eguía Martínez F, Río Torres M, Capote Cabrera A, Ríos Caso R, Hernández Silva JR, Gómez Cabrera CG. Manual de diagnóstico y tratamiento en Oftalmología [Internet]. La Habana: Editorial Ciencias Médicas; 2009. [acceso: 25/09/2024]. Disponible en: https://epdf.pub/manual-de-diagnostico-y-tratamiento-en-oftalmologia.html
16. Salmon JF. Kanski. Manual de oftalmología clínica. London, New York: Elsevier Health Sciences [Internet]. 2023 [acceso: 25/09/2024]; 472 p. Disponible en: https://archive.org/details/KanskisClinicalOphthalmology8th2016_201901
17. World Medical Association. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human participants [Internet]. JAMA. 2024; 33(1):71-74. DOI: http://dx.doi.org/10.1001/jama.2024.21972
18. Ministerio de Salud Pública. Anuario Estadístico de Salud 2022 [Internet]. La Habana: Dirección de Registros Médicos y Estadísticas de Salud; 2023. [acceso: 25/09/2024]. Disponible en: https://files.sld.cu/dne/files/2023/10/Anuario-Estadistico-de-Salud-2022-Ed-20231.pdf
19. Karaca U, Kucukevcilioglu M, Durukan AH, Akincioglu D. The effect of longstanding silicone oil on retina choroid and optic nerve in eyes with retinal detachment: an optical coherence tomography study [Internet]. BMC Ophthalmol. 2022; 22(1): 11. Disponible en: http://dx.doi.org/10.1186/s12886-021-02239-0
20. Ferrara M, Mehta A, Qureshi H, Avery P, Yorston D. Phenotype and Outcomes of Phakic Versus Pseudophakic Primary Rhegmatogenous Retinal Detachments: Cataract or Cataract Surgery Related? [Internet]. Am J Ophthalmol. 2021; 222: 318-27. DOI: http://dx.doi.org/10.1016/j.ajo.2020.09.03
21. Casswell EJ, Yorston D, Lee E, Heeren TFC, Harris N. Effect of face-down positioning vs support-the-break positioning after macula-involving retinal detachment repair: The PostRD randomized clinical trial [Internet]. JAMA Ophthalmol. 2020; 138(6): 634. DOI: http://dx.doi.org/10.1001/jamaophthalmol.2020.0997
22. Trivizki O, Zur D, Goldenberg D, Rabina G, Fleissig E, Barak A. A novel finding of hyperreflective material in the silicone-retina interface: An optical coherence tomographic and histopathological study [Internet]. Retina. 2020; 40(10): 2055–60. DOI: http://dx.doi.org/10.1097/IAE.0000000000002691
23. Nicolai M, Lassandro N, Franceschi A, Rosati A, De Turris S, Pelliccioni P. Intraocular pressure rise linked to silicone oil in retinal surgery. A review [Internet]. Vision (Basel). 2020; 4(3): 36. DOI: http://dx.doi.org/10.3390/vision4030036
24. Cisneros CM, Cruz C, Baluerdes CAB. Hipertensión ocular secundaria a aceite de silicona [Internet]. Revista Cubana de Oftalmología. 2022 [acceso: 25/09/2024]; 35(4): 1-11. Disponible en: https://www.medigraphic.com/pdfs/revcuboft/rco-2022/rco224s.pdf
25. Karasu B, Erıs E, Sonmez O, Bekmez S. The effect of silicone oil presence time on macular and choroidal thickness with macula-off rhegmatogenous retinal detachment [Internet]. J Fr Ophtalmol. 2020; 43(7): 626–34. DOI: http://dx.doi.org/10.1016/j.jfo.2019.10.017
26. Issa R, Xia T, Zarbin MA, Bhagat N. Silicone oil removal: post-operative complications [Internet]. EYE. 2020; 34(3): 537–43. DOI: http://dx.doi.org/10.1038/s41433-019-0551-7
27. Al-Nashar HY, Dabbour SA, Alnaimy MA. Retinal electrophysiological changes related to early versus late silicone oil removal [Internet]. Int Ophthalmol. 2021; 41(12):4075–82. DOI: http://dx.doi.org/10.1007/s10792-021-01980-1
28. Inan S, Polat O, Ozcan S, Inan UU. Comparison of long-term automated retinal layer segmentation analysis of the macula between silicone oil and gas tamponade after vitrectomy for rhegmatogenous retinal detachment [Internet]. Ophthalmic Res. 2020; 63(6): 524–32. DOI: http://dx.doi.org/10.1159/000506382
29. Valentín FJ, Mateos E, Usategui R, Andrés C, PastorJC, Pastor S. Inteligencia artificial y nuevos modelos de lenguaje en Oftalmología: Complicaciones del uso de aceite de silicona en cirugía vitreorretiniana [Internet]. Arch Soc Esp Oftalmología. 2023; 98(5): 298–303. DOI: http://dx.doi.org/10.1016/j.oftal.2023.03.010
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Ceija Molina Cisneros , Mario Jesús Pérez Benites , Rafael E. Ureña Gil , Iraisi Francisca Hormigó Puertas, Elizabeth Bárbara Cuétara
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Authors who have publications with this Journal accept the following terms:
- The authors will retain their copyright and guarantee the Journal the right of first publication of their work, which will simultaneously be subject to the Creative Commons Attribution License. The content presented here can be shared, copied and redistributed in any medium or format; Can be adapted, remixed, transformed or created from the material, using the following terms: Attribution (giving appropriate credit to the work, providing a link to the license, and indicating if changes have been made); non-commercial (you cannot use the material for commercial purposes) and share-alike (if you remix, transform or create new material from this work, you can distribute your contribution as long as you use the same license as the original work).
- The authors may adopt other non-exclusive license agreements for the distribution of the published version of the work (for example: depositing it in an institutional electronic archive or publishing it in a monographic volume) as long as the initial publication in this Journal is indicated.
- Authors are allowed and recommended to disseminate their work through the Internet (e.g., in institutional electronic archives or on their website) before and during the submission process, which can produce interesting exchanges and increase citations. of the published work.
