Primary uveal melanoma about a case
Keywords:
choroidal melanoma, ocular neoplasia, uveal melanomaAbstract
Introduction: Uveal melanoma is a rare condition that accounts for approximately 5% of all primary melanomas; the choroidal melanoma is the most common.
Objective: To describe, from a clinical and pathological point of view, a patient with choroidal melanoma.
Clinical case: A 58-year-old male patient with progressive vision loss of one year's duration is presented. Direct ophthalmoscopy revealed a tumor-like pigmented lesion in the right eye, in the choroid, which had grown into the vitreous cavity. A computed tomography scan showed a hyperdense image in the nasal area of the right eye. Based on clinical suspicion of uveal melanoma, right enucleation was performed. The biopsy confirmed the diagnosis of spindle cell B-type choroidal melanoma.
Conclusions: Understanding the clinical and pathological characteristics of uveal melanoma is crucial to increasing survival and improving the quality of life of affected patients. Early diagnosis and timely treatment help minimize the impact of this rare and fatal disease.
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1. Branisteanu DC, Bogdanici CM, Branisteanu DE, Maranduca MA, Zemba M, Balta F, et al. Uveal melanoma diagnosis and current treatment options (Review) [Internet]. Exp Ther Med. 2021; 22(6):1428. DOI: 10.3892/etm.2021.10863
2. Abudalu L, Malhotra V, Nasir N, Titi S. Metastatic choroidal melanoma in the breast: a case report and review of the literature [Internet]. J Pathol Transl Med. 2023; 57(4):238-41. DOI: 10.4132/jptm.2023.06.07
3. Teoh CY, W Md Kasim WM, Norlaila T. Choroidal Melanoma: A Case Series From Malaysia [Internet]. Cureus. 2022; 14(11):e31105. DOI: 10.7759cureus.31105
4. Piñón-García K, Almeida-Esquivel Y, Toledo-Cabarcos Y, González-Basulto MJ. Melanoma uveal [Internet]. Arch méd Camagüey. 2023 [acceso: 05/06/2025]; 27:e9347. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1025-02552023000100019&lng=es
5. Soliman N, Mamdouh D, Elkordi A. Choroidal Melanoma: A Mini Review [Internet]. Medicines (Basel). 2023;10(1):11. DOI: 10.3390medicines10010011
6. Di Luciano A, Adaniya A, Morales-Cantón V, Becerra E, Soberón V. Melanoma coroideo: revisión sistemática [Internet]. Oftalmol Clin Exp. 2020 [acceso: 05/06/2025]; 13(2):68-81. Disponible en: https://revistaoce.com/index.php/revista/article/view/15
7. Menéndez-Hernández YC, O'Relly-Noda D, Cutiño-Hernández K, Pérez-Gutiérrez Y, Ribot-Ruiz LA. Panoftalmitis: presentación atípica de un melanoma coroideo [Internet]. Rev Med Electrón. 2022 [acceso: 05/06/2025]; 44(1):227-37. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1684-18242022000100227&lng=es
8. Jiblawi A, Chanbour H, Tayba A, Khayat H, Jiblawi K. Magnetic Resonance Imaging Diagnosis of Choroidal Melanoma [Internet]. Cureus. 2021; 13(7):e16628. DOI: 10.7759/cureus.16628
9. Eberhart C. Eye and ocular adnexa. En: Goldblum J, Lamps L, McKenney J, Myers J. Rosai and Ackerman's Surgical Pathology, 11na ed. Filadelfia: ELSEVIER; 2018. p. 2132-4.
10. Obuchowska I, Konopińska J. Importance of Optical Coherence Tomography and Optical Coherence Tomography Angiography in the Imaging and Differentiation of Choroidal Melanoma: A Review. Cancers (Basel) [Internet]. 2022; 14(14):3354. DOI: 10.3390/cancers14143354
11. Márquez-Falcón A, Cabanes-Goy L, Artiles Martínez D. Estudio epidemiológico y anatomopatológico del melanoma uveal. Rev Cubana de Oftalmol [Internet]. 2022 [acceso: 05/06/2025];35(2):e1589. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-21762022000200005&Ing=es
12. Raval V, Luo S, Zabor E, Singh A. Small Choroidal Melanoma: Correlation of growth rate with Pathology [Internet]. Ocul Oncol Pathol. 2021; 7:401-10. DOI: 10.1159/000517203
13. Manchegowda P, Singh A, Shields C, Kaliki S, Shah P, Gopal L, et al. Uveal Melanoma in Asians: A Review [Internet]. Ocul Oncol Pathol. 2021; 7:159-67. DOI: 10.1159/000512738
14. López-Martínez AL, Bautista-Hernández Y, Moreno-Páramo D. Melanoma coroideo: reporte de casos y experiencia del Hospital General de México [Internet]. Gac Mex Oncol. 2022; 21(Supl):1-6. DOI: 10.24875/j.gamo.21000020
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Copyright (c) 2025 Alejandro Jarol Pavón Rojas, Lisvan Cisnero-Reyes, Dainel Antonio Blanco Fernández , Luvia Ines Vistorte Vistorte, Osleidys Rojas Silva
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