Kounis syndrome Type 1 in a patient with an allergic reaction to amoxicillin

Authors

Keywords:

allergic myocardial infarction, angina pectoris variant, hypersensitivity, Kounis syndrome

Abstract

Introduction: Kounis syndrome is a complex and potentially serious clinical entity characterized by the concurrent occurrence of an acute coronary syndrome and an allergic or hypersensitivity reaction.

Objective: To collect the clinical, electrocardiographic and imaging manifestations of Kounis syndrome in the context of an allergic reaction to amoxicillin.

Clinical Case: A 45-year-old male patient with a known history of penicillin allergy. The electrocardiogram revealed ST-segment elevation greater than 2 mm in leads II, III, and aVF, along with ST-segment depression in leads aVL and V2.

Conclusion: Kounis syndrome can present at any age and combines allergic reactions with cardiac involvement. Its management requires a careful balance between treating hypersensitivity and ensuring cardiovascular stability.

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Author Biographies

Lila Alicia Echevarría Sifontes, Hospital Docente Comandante Manuel Fajardo

Especialista de Primer Grado en Cardiología. Profesora Auxiliar

Luis Mariano de la Torre Fonseca, Hospital Docente Clínico Quirúrgico Comandante Manuel Fajardo

Especialista de Primer y Segundo Grado en Cardiología. Especialista de Primer Grado en Medicina General Integral. Profesor e Investigador Auxiliar

Adrian Mauricio Naranjo Pacheco, Hospital Clínica San Francisco. Guayaquil. Ecuador

Doctor en Medicina. Especialista en Cardiología

Henry David Suárez Arias, Clínica Sur Hospital

Doctor en Medicina.

Génesis Nicole Pezo Rodríguez, Clínica Sur Hospital

Doctora en Medicina

Alexer Torres Figuera, Instituto de Medicina Tropical "Pedro Kouri"

Especialista en Medicina Interna. Profesor Auxiliar.

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Published

2025-08-08

How to Cite

1.
Echevarría Sifontes LA, de la Torre Fonseca LM, Naranjo Pacheco AM, Suárez Arias HD, Pezo Rodríguez GN, Torres Figuera A. Kounis syndrome Type 1 in a patient with an allergic reaction to amoxicillin. Rev Cubana Med Milit [Internet]. 2025 Aug. 8 [cited 2025 Aug. 16];54(3):e025076509. Available from: https://revmedmilitar.sld.cu/index.php/mil/article/view/76509