Sealing Ability of Resilon as a Root Canal Filling Material: A Systematic Review of In Vitro Studies

Authors

Keywords:

Root Canal Filling Materials, In Vitro Techniques, Endodontics, Endodontic Obturation

Abstract

Objective: This systematic review aimed to evaluate the coronal and apical sealing ability of Resilon, a thermoplastic synthetic root canal filling material, compared to gutta-percha under in vitro conditions.

Methods: Following PRISMA-2020 guidelines, a comprehensive search was conducted across four databases (PubMed, Scopus, Web of Science, and Cochrane Library) without restrictions on language or publication date. Although both clinical and in vitro studies were deemed eligible, no clinical studies meeting the inclusion criteria were identified during the literature search. As a result, the final synthesis included exclusively in vitro investigations. Twenty-seven in vitro studies were included after duplicate removal, screening, and eligibility assessment. Two reviewers performed data extraction and risk of bias appraisal independently.

Results: Findings showed that Resilon exhibited superior sealing ability in 17 studies, particularly in terms of reduced microleakage and better adaptation to canal walls, especially when used with methacrylate-based sealers. However, seven studies reported no significant differences between Resilon and gutta-percha, and three studies showed inferior sealing with Resilon, especially in long-term storage or under adverse conditions. Risk of bias analysis revealed methodological concerns in several studies, particularly regarding confounding and outcome measurement. The results suggest that while Resilon may offers short-term advantages in controlled settings, its sealing capacity may decline over time, raising questions about its long-term reliability.

Conclusion: Overall, the evidence supports the potential use of Resilon in specific scenarios where immediate sealing is critical, but further standardized research and clinical trials are necessary to validate its long-term effectiveness and biocompatibility.

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References

1. Tait C, Camilleri J, Blundell K. Non-surgical endodontics – obturation [Internet]. British Dental Journal. 2025;238(7):487-96. DOI: https://doi.org/10.1038/s41415-025-8562-1

2. Fernandes AM, Prasad BK, Naik SS, Umesh S. Root canal sealers-a comprehensive review [Internet]. World Journal of Pharmaceutical Research. 2024;13(15):106-16. DOI: https://doi.org/10.20959/wjpr202415-33151

3. Lim M, Jung C, Shin D-H, Cho Y-b, Song M. Calcium silicate-based root canal sealers: a literature review [Internet]. Restor Dent Endod. 2020;45(3):e35. DOI: https://doi.org/10.5395/rde.2020.45.e35

4. Pandey P, Aggarwal H, Tikku AP, Singh A, Bains R, Mishra S. Comparative evaluation of sealing ability of gutta percha and resilon as root canal filling materials- a systematic review [Internet]. Journal of Oral Biology and Craniofacial Research. 2020;10(2):220-6. DOI: https://doi.org/10.1016/j.jobcr.2019.12.004

5. Camilleri J. Sealers and Warm Gutta-percha Obturation Techniques [Internet]. Journal of Endodontics. 2015;41(1):72-8. DOI: https://doi.org/10.1016/j.joen.2014.06.007

6. Strange KA, Tawil PZ, Phillips C, Walia HD, Fouad AF. Long-term Outcomes of Endodontic Treatment Performed with Resilon/Epiphany [Internet]. J Endod. 2019;45(5):507-12. DOI: https://doi.org/10.1016/j.joen.2019.01.019

7. Cotton TP, Schindler WG, Schwartz SA, Watson WR, Hargreaves KM. A Retrospective Study Comparing Clinical Outcomes after Obturation with Resilon/Epiphany or Gutta-Percha/Kerr Sealer [Internet]. Journal of Endodontics. 2008;34(7):789-97. DOI: https://doi.org/10.1016/j.joen.2008.03.018

8. Lotfi M, Ghasemi N, Rahimi S, Vosoughhosseini S, Saghiri MA, Shahidi A. Resilon: a comprehensive literature review [Internet]. J Dent Res Dent Clin Dent Prospects. 2013;7(3):119-30. DOI: https://doi.org/10.5681/joddd.2013.020

9. Shanahan DJ, Duncan HF. Root canal filling using Resilon: A review [Internet]. British Dental Journal. 2011;211(2):81-8. DOI: https://doi.org/10.1038/sj.bdj.2011.573

10. Tan M, Chai Z, Sun C, Hu B, Gao X, Chen Y, et al. Comparative evaluation of the vertical fracture resistance of endodontically treated roots filled with Gutta-percha and Resilon: a meta-analysis of in vitro studies [Internet]. BMC Oral Health. 2018;18(1):107. DOI: https://doi.org/10.1186/s12903-018-0571-x

11. Li G, Li Y, He J, Liu S, Tang J, Jiao T, et al. Comparative assessment of vertical fracture resistance in endodontically treated roots with different obturating systems and techniques: a systematic review and network meta-analysis of in vitro studies [Internet]. BMC Oral Health. 2024;24(1):1439. DOI: https://doi.org/10.1186/s12903-024-05111-x

12. Tanomaru-Filho M, Pinto RVS, Bosso R, Nascimento CA, Berbert FLCV, Guerreiro-Tanomaru JM. Evaluation of the thermoplasticity of gutta-percha and Resilon® using the Obtura II System at different temperature settings [Internet]. International Endodontic Journal. 2011;44(8):764-8. DOI: https://doi.org/10.1111/j.1365-2591.2011.01889.x

13. Attam K, Talwar S. A laboratory comparison of apical leakage between immediate versus delayed post space preparation in root canals filled with Resilon [Internet]. International Endodontic Journal. 2010;43(9):775-81. DOI: https://doi.org/10.1111/j.1365-2591.2010.01742.x

14. Biggs S, Knowles K, Ibarrola J, Pashley D. An in vitro assessment of the sealing ability of resilon/epiphany using fluid filtration [Internet]. J Endod 2006;32(8):759-61. DOI: https://doi.org/10.1016/j.joen.2005.08.013

15. Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews [Internet]. BMJ. 2021;372:n71. DOI: https://doi.org/10.1136/bmj.n71

16. Onay E, Ungor M, Orucoglu H. An in vitro evaluation of the apical sealing ability of a new resin-based root canal obturation system [Internet]. J Endod. 2006;32(10):976-8. DOI: https://doi.org/10.1016/j.joen.2006.05.013

17. Pitout E, Oberholzer TG, Blignaut E, Molepo J. Coronal Leakage of Teeth Root-Filled With Gutta-Percha or Resilon Root Canal Filling Material [Internet]. Journal of Endodontics. 2006;32(9):879-81. DOI: https://doi.org/10.1016/j.joen.2006.02.004

18. Wang C, Debelian G, Teixeira F. Effect of intracanal medicament on the sealing ability of root canals filled with Resilon [Internet]. Journal of endodontics. 2006;32(6):532-6. DOI: https://doi.org/10.1016/j.joen.2005.11.002

19. Kaya B, Kececi A, Belli S. Evaluation of the sealing ability of gutta-percha and thermoplastic synthetic polymer-based systems along the root canals through the glucose penetration model [Internet]. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 2007;104(6):e66-73. DOI: https://doi.org/10.1016/j.tripleo.2007.06.024

20. Al-Maswary AA, Alhadainy HA-H, Al-Maweri SA. Coronal microleakage of the resilon and gutta-percha obturation materials with epiphany se sealer: An invitro study [Internet]. Journal of Clinical and Diagnostic Research. 2016;10(5):ZC39-ZC42. DOI: https://doi.org/10.7860/JCDR/2016/17545.7750

21. Eroğlu MG, Bayırlı GŞ. The comparison of dentin adaptation and sealing ability of gutta-percha/AH plus, resilon/epiphany SE, EndoREZ: An in-vitro study [Internet]. Eastern Journal of Medicine. 2017;22(4):155-61. DOI: https://doi.org/10.5505/ejm.2017.86580

22. Vula V, Ajeti N, Kuçi A, Stavileci M, Vula V, Vula V, et al. An In Vitro Comparative Evaluation of Apical Leakage Using Different Root Canal Sealers [Internet]. Medical Science Monitor Basic Research. 2020;26. DOI: https://doi.org/10.12659/MSMBR.928175

23. Paqué F, Sirtes G. Apical sealing ability of Resilon/Epiphany versus gutta-percha/AH Plus: immediate and 16-months leakage [Internet]. International endodontic journal. 2007;40(9):722-9. DOI: https://doi.org/10.1111/j.1365-2591.2007.01298.x

24. Kececi A, Kaya B, Belli S, Kececi AD, Kaya BU, Belli S. Corono-apical Leakage of Various Root Filling Materials Using Two Different Penetration Models-A 3-Month Study [Internet]. Journal Of Biomedical Materials Research Part B-Applied Biomaterials. 2010;92(1):261-7. DOI: https://doi.org/10.1002/jbm.b.31513

25. Santos J, Tjäderhane L, Ferraz C, Zaia A, Alves M, De Goes M, et al. Long-term sealing ability of resin-based root canal fillings [Internet]. International Endodontic Journal. 2010;43(6):455-60. DOI: https://doi.org/10.1111/j.1365-2591.2010.01687.x

26. Prithviraj K, Manjunatha R, Horatti P, Rao N, Gokul S. In Vitro comparison of the microbial leakage of obturation systems: Epiphany with resilon, guttaflow, and ah plus with gutta percha [Internet]. Indian Journal of Dental Research. 2020;31(1):37-41. DOI: https://doi.org/10.4103/ijdr.IJDR_98_18

27. Bodrumlu E, Tunga U. Apical leakage of Resilon™ obturation material [Internet]. Journal of Contemporary Dental Practice. 2006;7(4):045-52. DOI: https://doi.org/10.5005/jcdp-7-4-45

28. Fathia E, Abu-Bakr NH, Yahia I. A comparative study of the microleakage of resilon/epiphany and gutta-percha/AH-Plus obturating systems [Internet]. Iranian Endodontic Journal. 2012 [acceso: 11/04/2025];7(3):139-43. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3467139/

29. Lambor RT, De Noronha De Ataide I, Chalakkal P, Akkara F, Shariff SA, Fernandes KS. An in vitro comparison between the apical sealing abilities of resilon with Epiphany® sealer and gutta-percha with AH plus sealer [Internet]. Indian Journal of Dental Research. 2012;23(5):694. DOI: https://doi.org/10.4103/0970-9290.107415

30. Veríssimo DM, Sampaio do Vale M, Monteiro AJ. Comparison of Apical Leakage between Canals Filled with Gutta-Percha/AH-Plus and the Resilon/Epiphany System, When Submitted to Two Filling Techniques [Internet]. J Endod. 2007;33(3):291-4. DOI: https://doi.org/10.1016/j.joen.2006.10.014

31. Shipper G, Ørstavik D, Teixeira FB, Trope M. An evaluation of microbial leakage in roots filled with a thermoplastic synthetic polymer-based root canal filling material (Resilon) [Internet]. J Endod. 2004;30(5):342-7. DOI: https://doi.org/10.1097/00004770-200405000-00009

32. Pasqualini D, Scotti N, Mollo L, Berutti E, Angelini E, Migliaretti G, et al. Microbial leakage of gutta-percha and Resilon™ root canal filling material: A comparative study using a new homogeneous assay for sequence detection [Internet]. Journal Of Biomaterials Applications. 2008;22(4):337-52. DOI: https://doi.org/10.1177/0885328207077411

33. De Bruyne M, De Moor R, De Bruyne MAA, De Moor RJG. Long-term sealing ability of Resilon apical root-end fillings [Internet]. International Endodontic Journal. 2009;42(10):884-92. DOI: https://doi.org/10.1111/j.1365-2591.2009.01583.x

34. Zmener O, Pameijer C, Serrano S, Vidueira M, Macchi R, Zmener O, et al. Significance of moist root canal dentin with the use of methacrylate-based endodontic sealers: An in vitro coronal dye leakage study [Internet]. Journal Of Endodontics. 2008;34(1):76-9. DOI: https://doi.org/10.1016/j.joen.2007.10.012

35. Almeida J, Gomes B, Ferraz C, Souza-Filho F, Zaia A. Filling of artificial lateral canals and microleakage and flow of five endodontic sealers [Internet]. International endodontic journal. 2007;40(9):692-9. DOI: https://doi.org/10.1111/j.1365-2591.2007.01268.x

36. Baumgartner G, Zehnder M, Paqué F. Enterococcus faecalis type strain leakage through root canals filled with Gutta-Percha/AH plus or Resilon/Epiphany [Internet]. J Endod 2007;33(1):45-7. DOI: https://doi.org/10.1016/j.joen.2006.08.002

37. Hammad M, Qualtrough A, Silikas N, Hammad M, Qualtrough A, Silikas N. Evaluation of Root Canal Obturation: A Three-dimensional In Vitro Study [Internet]. J Endod. 2009;35(4):541-4. DOI: https://doi.org/10.1016/j.joen.2008.12.021

38. Kqiku L, Städtler P, Gruber H, Baraba A, Anic I, Miletic I, et al. Active versus passive microleakage of Resilon/Epiphany and gutta-percha/AH Plus [Internet]. Australian Endodontic Journal. 2011;37(3):141-6. DOI: https://doi.org/10.1111/j.1747-4477.2010.00238.x

39. Nawal R, Parande M, Sehgal R, Rao N, Naik A, Nawal RR, et al. A comparative evaluation of 3 root canal filling systems [Internet]. Oral Surgery Oral Medicine Oral Pathology Oral Radiology And Endodontology. 2011;111(3):387-93. DOI: https://doi.org/10.1016/j.tripleo.2010.09.070

40. Abdo SB, Darrat AA, Masudi SM, Luddin N, Husien A. Sealing ability of gutta-percha/nano HA versus resilon/epiphany after 20 months using an electrochemical model - an in vitro study [Internet]. Brazilian Journal of Oral Sciences. 2012 [acceso: 11/04/2025];11(3):387-91. Available from: https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641375

41. Kangarlou A, Dianat O, Esfahrood Z, Asharaf H, Zandi B, Eslami G, et al. Bacterial leakage of GuttaFlow-filled root canals compared with Resilon/Epiphany and Gutta-percha/AH26-filled root canals [Internet]. Australian Endodontic Journal. 2012;38(1):10-3. DOI: https://doi.org/10.1111/j.1747-4477.2010.00267.x

42. Shrestha D, Wei X, Wu WC, Ling JQ. Resilon: A methacrylate resin-based obturation system [Internet]. J Dent Sci. 2010;5(2):47-52. DOI: https://doi.org/10.1016/S1991-7902(10)60008-6

43. Soares C, Maia C, Vale F, Gadê-Neto C, Carvalho L, Oliveira H, et al. Comparison of endodontic retreatment in teeth obturated with resilon or gutta-percha: A review of literature [Internet]. Iranian Endodontic Journal. 2015;10(4):221-5. DOI: https://doi.org/10.7508/iej.2015.04.002

44. Hirai VHG, da Silva Neto UX, Westphalen VPD, Perin CP, Carneiro E, Fariniuk LF. Comparative analysis of leakage in root canal fillings performed with gutta-percha and Resilon cones with AH Plus and Epiphany sealers [Internet]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(2):e131-e5. DOI: https://doi.org/10.1016/j.tripleo.2009.09.038

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Published

2025-08-19

How to Cite

1.
Chaple-Gil AM, Ortiz Santiago LL, Pereda Vázquez L, Santiesteban Velázquez M. Sealing Ability of Resilon as a Root Canal Filling Material: A Systematic Review of In Vitro Studies. Rev Cubana Med Milit [Internet]. 2025 Aug. 19 [cited 2025 Aug. 21];54(3):e025076716. Available from: https://revmedmilitar.sld.cu/index.php/mil/article/view/76716