Socio-demographic factors associated with the frequency of self-medication in university students in Lima
Keywords:
questionnaire; self-medication; sociodemographic factors; university studentsAbstract
Introduction: Self-medication is a public health problem and has a high prevalence among university students.
Objectives: Identifying sociodemographic factors associated with the frequency of self-medication in university students in Lima.
Methods: This observational, analytical, and cross-sectional study was conducted between October and December 2023 with 232 students selected by convenience sampling. The frequency of self-medication was assessed using a validated 12-item questionnaire and categorized into three types: never, sometimes, and always. Sociodemographic factors included sex, age group, year of study, marital status, place of origin, area of residence, having children, and occupation. Bivariate analysis was performed using the chi-square test, and multivariate analysis was conducted using a logit model, estimating odds ratios (OR) with 95% confidence intervals. A p-value < 0.05 was considered statistically significant.
Results: 69.40% of participants reported self-medicating, with "sometimes" being the most frequent category (60.78%). Multivariable analysis identified being a third-year student (OR = 0.037) and being solely dedicated to studying (OR = 0.154) as protective factors. Female sex (OR = 46.758) and residing in a rural area (OR = 5.713) were associated with a higher risk of self-medication. No significant associations were found with age, marital status, place of origin, or having children (p > 0.05).
Conclusions: Self-medication has a high prevalence, consistent with what has been reported in other university populations, and shows a statistical association with year of study, occupation, sex, and area of residence.
Downloads
References
1. Khan SD, Al-Garni M, Alalhareth FA, Al Touk AA, Al-Ajmi HA, Alyami SA, et al. Data on self-medication among healthcare students at Najran University, KSA [Internet]. Bioinformation. 2021 [acceso: 10/02/2026];17(5):599–607. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770411/
2. Loni SB, Eid Alzahrani R, Alzahrani M, Khan MO, Khatoon R, Abdelrahman HH, et al. Prevalence of self-medication and associated factors among female students of health science colleges at Majmaah University: A cross-sectional study [Internet]. Front Public Health. 2023 [acceso: 10/02/2026];11:1090021. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978380/
3. Urbina A, Morales-Cortés M, Mendoza-Romero D, Pérez-Acosta A. The epidemiology of self-medication in Colombia: A systematic literature review and meta-analysis [Internet]. Rev. Colomb. Cienc. Quim. Farm. 2023 [acceso: 10/02/2026];52(3): 1183-1207. Disponible en: https://revistas.unal.edu.co/index.php/rccquifa/article/view/110393
4. Pacha A, De la Torre A, Guangasig V, Hidalgo K. Automedicación: un enfoque de revisión sobre sus riesgos, consecuencias y una práctica responsable [Internet]. LATAM Revista Latinoamericana De Ciencias Sociales y Humanidades. 2023 [acceso: 10/02/2026];4(4):708-21. Disponible en: https://latam.redilat.org/index.php/lt/article/view/1252
5. Kumar A, Vandana, Aslami AN. Analgesics Self-Medication and its Association with Sleep Quality among Medical Undergraduates [Internet]. J Clin of Diagn Res. 2016 [acceso: 10/02/2026];10(12):F07-F11. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296445
6. Castro-Cataño ME, Pechené-Paz PA, Rocha-Tenorio VE, Loaiza-Buitrago DF. Automedicación en estudiantes de pregrado de enfermería [Internet]. Enferm. glob. 2022 [acceso: 10/02/2026];21(66):274-301. Disponible en: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1695-61412022000200274&lang=es#B3
7. Tomas Petrović A, Pavlović N, Stilinović N., Lalović N, Paut Kusturica M, Dugandžija T, et al. Self-Medication Perceptions and Practice of Medical and Pharmacy Students in Serbia [Internet]. Int J Environ Res Public Health. 2022 [acceso: 10/02/2026];19(3):1193. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834465/
8. Urrunaga-Pastor D, Benites-Zapata VA and Mezones-Holguín E. Factors associated with self-medication in users of drugstores and pharmacies in Peru: an analysis of the National Survey on User Satisfaction of Health Services, ENSUSALUD 2015 [Internet]. F1000Res. 2019 [acceso: 10/02/2026];8:23. Disponible en: https://pubmed.ncbi.nlm.nih.gov/32089820/
9. Rahimisadegh R, Sharifi N, Jahromi VK, Zahedi R, Rostayee Z, Asadi R. Self-medication practices and their characteristics among Iranian university students [Internet]. BMC Pharmacol Toxicol. 2022 [acceso: 10/02/2026];23(1):60. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358361/
10. Esan DT, Fasoro AA, Odesanya OE, Esan TO, Ojo EF, Faeji CO. Assessment of self-medication practices and its associated factors among undergraduates of a private university in Nigeria [Internet]. J Environ Public Health. 2018 [acceso: 10/02/2026];2018:1–7. Disponible en: https://pubmed.ncbi.nlm.nih.gov/30671097/
11. Zewdie S, Andargie A, Kassahun H. Self-medication practices among undergraduate university students in northeast Ethiopia [Internet]. Risk Manag Healthc Policy. 2020 [acceso: 10/02/2026];13:1375–81. Disponible en: https://pubmed.ncbi.nlm.nih.gov/32922102/
12. Maslat A, Al-Atoom N, Al-Najdawi M, Hassouneh LK, Mashaal A, Alrashdan Y, et al. Drug misuse and self-medication among pharmacy students in Jordan [Internet]. Pol Merkur Lekarski. 2023 [acceso: 10/02/2026];51(5):464–74. Disponible en: https://pubmed.ncbi.nlm.nih.gov/38069846/
13. Amponsah SK, Odamtten G, Adams I, Kretchy IA. A comparative analysis of pattern and attitude towards self-medication among pharmacy and non-pharmacy students in University of Ghana [Internet]. Pan Afr Med J. 2022 [acceso: 10/02/2026];41:254. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188003/
14. Alshammari F, Alobaida A, Alshammari A, Alharbi A, Alrashidi A, Almansour A, et al. University students’ self-medication practices and pharmacists role: A cross-sectional survey in hail, Saudi Arabia [Internet]. Front Public Health. 2021 [acceso: 10/02/2026];9:779107. Disponible en: https://pubmed.ncbi.nlm.nih.gov/34976931/
15. Ghaferi AA, Schwartz TA, Pawlik TM. STROBE Reporting Guidelines for Observational Studies [Internet]. JAMA Surg. 2021 [acceso: 10/02/2026];156(6):577-8. Disponible en: https://jamanetwork.com/journals/jamasurgery/article-abstract/2778474
16. Gamboa Graus ME. Estadística aplicada a la investigación educativa [Internet]. Revista Dilemas Contemporáneos: Educación, política y valores. 2018 [acceso: 10/02/2026];5(2):1-32. Disponible: https://dilemascontemporaneoseducacionpoliticayvalores.com/index.php/dilemas/article/view/427
17. Fetensa G, Tolossa T, Etafa W, Fedaku G. Prevalence and predictors of self-medication among university students in Ethiopia: a systematic review and meta-analysis [Internet]. J of Pharm Policy and Pract. 2021 [acceso: 10/02/2026];14(1):107. Disponible en: https://link.springer.com/article/10.1186/s40545-021-00391-y#citeas
18. Azócar P, Valdés-González M, Garrido-Suárez B, Fernández-Alonso M, Garrido G. Self-medication in students of medical and biological sciences careers [Internet]. J. Pharm. Pharmacogn. Res. 2023 [acceso: 10/02/2026];11(6):1079-1105. Disponible en: https://jppres.com/jppres/self-medication-in-students-of-medical-and-biological-sciences-careers/
19. Izadpanah F, Bouya S, Gazerani A, Rafiemanesh H, Balouchi A, Al-Mawali A, et al. Self-medication among medical students: a systematic review and meta-analysis of prevalence, causes, common drugs, and sources of information [Internet]. SA Pharmaceutical Journal. 2024 [acceso: 10/02/2026];91(1):39-55. Disponible en: https://journals.co.za/doi/abs/10.10520/ejc-mp_sapj_v91_n1_a8
20. Flores-Montalvo E, Córdova-Limaylla N, Ladera-Castañeda M, López-Gurreonero C, Echavarría-Gálvez A, Cornejo-Pinto A, et al. Factors associated with knowledge about pharmacological management of pregnant women in Peruvian dental students: a logistic regression analysis [Internet]. BMC Med Educ. 2023 [acceso: 10/02/2026];23(1):1-10. Disponible en: https://bmcmededuc.biomedcentral.com/articles/10.1186/s12909-023-04068-9#citeas
21. Pizarro K, Martínez O. Análisis factorial exploratorio mediante el uso de las medidas de adecuación muestral kmo y esfericidad de bartlett para determinar factores principales [Internet]. Journal of Science and Research. 2020 [acceso: 10/02/2026]; 5(CININGEC2020): 903-24. Disponible en: https://revistas.utb.edu.ec/index.php/sr/article/view/1046
22. Gutierrez-Quevedo Y, Ladera-Castañeda M, Castro-Rojas M, Huamani-Echaccaya J, Romero-Velásquez L, Aroste-Andía R, et al. Factors associated with scientific production conditions among dental students from the Peruvian capital: an analysis under a multivariable regression model [Internet]. BMC Med Educ. 2024 [acceso: 10/02/2026];24(1):1148. Disponible en: https://bmcmededuc.biomedcentral.com/articles/10.1186/s12909-024-06171-x#citeas
23. Escobedo M, Hernández J, Estebané O, Martínez G. Modelos de ecuaciones estructurales: Características, fases, construcción, aplicación y resultados [Internet]. Cienc Trab. 2016 [acceso: 10/02/2026];18(55):16-22. Disponible en: https://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-24492016000100004
24. Yucel SC, Ergin E, Orgun F, Gokcen M, Eser I. Validity and reliability study of the Moral Distress Questionnaire in Turkish for nurses [Internet]. Rev. Latino-Am. Enfermagem. 2020 [acceso: 10/02/2026];28:e3319. Disponible en: https://www.scielo.br/j/rlae/a/MSDhs5HTWk6kbkNC4MQCZdc/?format=pdf&lang=es
25. Verástegui-Sandoval A, Aquiles-Barzola F, Machco-Pasmiño H, Ladera-Castañeda M, Briceño-Vergel G, Castro-Rojas M, et al. Fear of COVID-19 associated with burnout syndrome in dentists of the Health Directorate of the National Police of Peru: a cross-sectional study at national level under multivariable regression model [Internet]. BMC Public Health. 2024 [acceso: 10/02/2026];24(1):1488. Disponible en: https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-024-18979-9#Fun
26. Cerda J, Villarroel L. Evaluación de la concordancia inter-observador en investigación pediátrica: Coeficiente de Kappa [Internet]. Rev. Chil. Pediatr. 2008 [acceso: 10/02/2026];79(1):54-58. Disponible en: https://www.scielo.cl/scielo.php?pid=S0370-41062008000100008&script=sci_arttext
27. Ladera-Castañeda M, León-Málaga F, Espinoza-Olórtegui M, Nicho-Valladares M, Cervantes-Ganoza L, Verástegui-Sandoval A, et al. actors associated with the perception of university professors about academic dishonesty in dental students from two peruvian universities: analysis under multivariable regression model [Internet]. BMC Med Educ. 2023 [acceso: 10/02/2026];23(1):297. Disponible en: https://bmcmededuc.biomedcentral.com/articles/10.1186/s12909-023-04281-6#citeas
28. Soto A, Cvetkovich A. Estudios de casos y controles [Internet]. Rev. Fac. Med. Hum. 2020 [acceso: 10/02/2026];20(1):138-143. Disponible en: http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S2308-05312020000100138
29. Pate A, Riley RD, Collins GS, van Smeden M, Van Calster B, Ensor J, et al. Minimum sample size for developing a multivariable prediction model using multinomial logistic regression [Internet]. Stat. Methods Med. Res. 2023 [acceso: 10/02/2026];32(3):555-71. Disponible en: https://pubmed.ncbi.nlm.nih.gov/36660777/
30. Hernández Merino A. Declaración de Helsinki: principios éticos de la investigación médica con seres humanos. Revisión de 2024 [Internet]. Rev Pediatr Aten Primaria. 2024 [acceso: 10/02/2026];26:439-43. Disponible en: https://pap.es/articulo/14260/declaracion-de-helsinki-principios-eticos-de-la-investigacion-medica-con-seres-humanos-revision-de-2024
31. Hernández-Vásquez A, Visconti-López F, Solorzano-Salazar D, Barrenechea-Pulache A. Prevalence and factors associated with self-medication for COVID-19 prevention using disproven drugs in Peru: a cross-sectional nationwide study [Internet]. Pharm Pract. 2024 [acceso: 10/02/2026];21(4):1-10. Disponible en: https://www.pharmacypractice.org/index.php/pp/article/view/2877
32. Durán CE, Cañás M, Urtasun MA, Elseviers M, Andia T, Vander Stichele R, et al. Regulatory reliance to approve new medicinal products in Latin American and Caribbean countries [Internet]. Rev Panam Salud Publica. 2021 [acceso: 10/02/2026];45:e10. Disponible en: https://iris.paho.org/bitstream/handle/10665.2/53563/v45e102021.pdf?sequence=1&isAllowed=y
33. Zevallos L, Borja C, Vásquez E, Palacios M, Vílchez M. Factores relacionados con la automedicación en estudiantes de ciencias de la salud [Internet]. Universidad y Sociedad. 2022 [acceso: 10/02/2026];14(3):460-468. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S2218-36202022000300460
34. Osorio J, Romero S. Realidades de la práctica de automedicación en estudiantes de la Universidad del Magdalena [Internet]. Enferm glob. 2021 [acceso: 10/02/2026];20(62):531-543. Disponible en: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1695-61412021000200016
35. Guevara Cieza GF, Vara Huaman LA. Automedicación en estudiantes de enfermería en una Universidad de Lima Norte, 2023 [Internet]. [Tesis de pregrado]. Lima: Universidad de Ciencias y Humanidades, Facultad de Ciencias de la Salud; 2024. [acceso: 10/02/2026]. Disponible en: https://repositorio.uch.edu.pe/jspui/handle/20.500.12872/914
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Héctor Alexander Vílchez-Cáceda, Karla Hortencia Bernal-Málaga, Carolina Mayo Takahashi-Ferrer, Milagros del Rosario Cortez-Rebatta, Ketty Rojas-Berastein, Pablo Jair Moreto-Huaman

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Authors who have publications with this Journal accept the following terms:
- The authors will retain their copyright and guarantee the Journal the right of first publication of their work, which will simultaneously be subject to the Creative Commons Attribution License. The content presented here can be shared, copied and redistributed in any medium or format; Can be adapted, remixed, transformed or created from the material, using the following terms: Attribution (giving appropriate credit to the work, providing a link to the license, and indicating if changes have been made); non-commercial (you cannot use the material for commercial purposes) and share-alike (if you remix, transform or create new material from this work, you can distribute your contribution as long as you use the same license as the original work).
- The authors may adopt other non-exclusive license agreements for the distribution of the published version of the work (for example: depositing it in an institutional electronic archive or publishing it in a monographic volume) as long as the initial publication in this Journal is indicated.
- Authors are allowed and recommended to disseminate their work through the Internet (e.g., in institutional electronic archives or on their website) before and during the submission process, which can produce interesting exchanges and increase citations. of the published work.

