Surgical outcome of endoscopic endonasal approaches in pituitary adenomas over 15 years

Authors

Keywords:

neuroendoscopy, pituitary adenoma, skull base.

Abstract

Introduction: Pituitary adenomas are common tumors of the sellar region. Surgical resection using endoscopic endonasal approaches constitutes an effective therapeutic option; with a low rate of postoperative morbidity and adequate imaging, endocrinological and ophthalmological control.
Objective: To describe the results of the use of endoscopic endonasal approaches in patients with pituitary adenomas.
Methods: A cross-sectional study was carried out that included 574 patients at the Hermanos Ameijeiras Hospital with a diagnosis of pituitary adenomas who underwent surgery using endoscopic endonasal approaches, in the period from 2009 to 2023. Variables were evaluated: sociodemographic, imaging and histopathological of the tumors, degree of surgical resection, postoperative control and complications. For data analysis, absolute and relative frequencies were used as summary measures.
Results: A 91.3% tumor resection was reported, with endocrinological control in 90.1% and ophthalmological improvement in 87.6%. In relation to the main complications, the following were identified: transient diabetes insipidus 4.0%, hypopituitarism 2.6% and cerebrospinal fluid fistula 2.1%.
Conclusions: Endoscopic endonasal approaches for pituitary adenomas are safe and effective surgical procedures with a low incidence of complications.

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Author Biographies

Omar López Arbolay, Hospital Clínico Quirúrgico Hermanos "Ameijeiras"

Neurocirujano, Jefe del servicio de Neurocirugía del hospital Clínico Quirúrgico Hermanos " Ameijeiras"

Marlon Manuel Ortiz Machín, Hospital Clínico Quirúrgico Hermanos "Ameijeiras"

Neurocirujano, servicio de Neurocirugía del hospital Clínico Quirúrgico Hermanos " Ameijeiras"

Carlos Roberto Vargas Gálvez, Hospital Clínico Quirúrgico Hermanos "Ameijeiras"

Neurocirujano, servicio de Neurocirugía del hospital Clínico Quirúrgico Hermanos " Ameijeiras"

Adriana Vivian Varela Baró, Hospital Clínico Quirúrgico Hermanos "Ameijeiras"

Neurocirujana, servicio de Neurocirugía del hospital Clínico Quirúrgico Hermanos " Ameijeiras"

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Published

2024-06-28

How to Cite

1.
López Arbolay O, Ortiz Machín MM, Vargas Gálvez CR, Varela Baró AV. Surgical outcome of endoscopic endonasal approaches in pituitary adenomas over 15 years. Rev Cubana Med Milit [Internet]. 2024 Jun. 28 [cited 2025 Apr. 3];53(3):e024017888. Available from: https://revmedmilitar.sld.cu/index.php/mil/article/view/17888

Issue

Vol. 53 No. 3 (2024): July - September

Section

Clinical Practice Article

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