Description of the association between periodontitis and COVID-19

Authors

Keywords:

association, COVID-19, periodontitis, two-way relationship.

Abstract

Introduction: Periodontitis is a chronic inflammatory disease characterized by loss of attachment with concomitant bone resorption and deepened grooves due to apical migration of the junctional epithelium. Viruses may participate in its pathogenesis; infectious agents unique in biology, including the SARS-CoV-2 that causes the COVID-19. Therefore, researchers have proposed theories that try to explain the possible association of this virus with periodontitis, considering that a bidirectional relationship exists between both. A bibliographic review on this topic was carried out from January 2021 to May 2023, using Google Scholar, the PubMed, SciELO, ScienceDirect, MEDLINE and LILACS databases.
Objective: Describe the available information on the association between periodontitis and COVID-19.
Development: In periodontitis, poor oral hygiene produces a dysbiosis of the oral microbiome that triggers the appearance of periodontopathogens; The entry of the SARS-CoV-2 can subvert the immune system, which causes a serious association of periodontal diseases with COVID-19. This virus can interact with the oral microbiome and cause excessive growth of pathobionts that aggravate the formation of periodontal pockets.
Conclusions: It is considered that the association between the disease caused by the SARS-CoV-2 with periodontitis is bidirectional, the effect of the virus on the immune system can aggravate periodontitis and the effects of chemical mediators of periodontitis make it more vulnerable the patient infected by SARS-CoV-2 to develop a coinfection.

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Published

2024-05-02

How to Cite

1.
Gregorio Duliep E, Rodríguez Guerra Y de la C, Díaz Montalvo G, González Rodríguez EZ. Description of the association between periodontitis and COVID-19. Rev Cubana Med Milit [Internet]. 2024 May 2 [cited 2025 Apr. 3];53(2):e024020455. Available from: https://revmedmilitar.sld.cu/index.php/mil/article/view/20455

Issue

Vol. 53 No. 2 (2024): April - June

Section

Review Article

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