Effectiveness of peridural and paravertebral ozone therapy in the treatment of lumbar discs herniations
Keywords:
intervertebral disc displacement, low back pain, ozone therapy.Abstract
Introduction: Lumbosacral pain is an important health problem that constitutes the second most frequent cause of medical care. It is due to osteodegenerative changes of the spine, among which are discs herniations. The highest prevalence is found in people between 30 and 50 years of age, more frequently in the male sex.Objective: To evaluate the effectiveness of transacral and paravertebral peridural ozone therapy in lumbar disc herniations.
Methods: A quasi-experimental study was performed in 55 patients with a diagnosis of degenerative lumbar disc herniation who attended the neurosurgery office and received treatment with paravertebral and transacro peridural ozone therapy over a period of one year. The behavior of pain before and after treatment was studied.
Results: More patients with multiple discs herniations were detected, especially the association of discopathies of the intervertebral spaces L4-L5 and L5-S1 and stenosis of the spinal canal. Treatment results according to the Macnab scale were good or sufficient in most cases. After the application of ozone therapy, the 94.5 % of the patients showed improvement in pain according to the Visual Analog Scale.
Conclusions: The treatment is useful in both single and multiple lumbar disc herniations, as well as in lumbar spinal canal stenosis; and the most effective and least innocuous way of use is the transacro caudal epidural.
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References
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2. Sconza C, Leonardi G, Kon E, Respizzi S, Massazza G, Marcacci M, et al. Oxygen-ozone therapy for the treatment of low back pain: a systematic review of randomized controlled trials [Internet]. Eur Rev Med Pharmacol Sci. 2021 [acceso: 13/08/2023]; 25:6034-46. Disponible en: https://www.europeanreview.org/wp/wp-content/uploads/6034-6046.pdf
3. Erario MÁ, Croce E, Moviglia Brandolino MT, Moviglia G, Grangeat AM. Ozone as Modulator of Resorption and Inflammatory Response in Extruded Nucleus Pulposus Herniation. Revising Concepts. Int J Mol Sci [Internet]. 2021 [acceso: 13/08/2023]; 22(18):9946. Disponible en: https://www.mdpi.com/1422-0067/22/18/9946
4. Somma F, D'Agostino V, Negro A, Piscitelli V, Tamburrini S, Sicignano C, et al. Radiation exposure and clinical outcome in patients undergoing percutaneous intradiscal ozone therapy for disc herniation: Fluoroscopic versus conventional CT guidance [Internet]. PLoS One. 2022; 17(3):e0264767. DOI: 10.1371/journal.pone.0264767
5. Akkawi I. Ozone therapy for musculoskeletal disorders Current concepts. Acta Biomed [Internet]. 2020; 91(4):e2020191. DOI: 10.23750/abm.v91i4.8979
6. López Batista D. Efectividad de la ozonoterapia por vía rectal en pacientes con hernia discal lumbar en el Servicio Provincial de Medicina Natural y Tradicional [Internet]. Ambiomed. [Tesis de terminación de la especialidad]. Universidad de Ciencias Médicas de Granma, Facultad de Ciencias Médicas de Bayamo; 2021 [acceso: 13/08/2023]. Disponible en: https://ambimed2021.sld.cu/index.php/ambimed/2021/paper/view/463/140
7. Kelekis A, Bonaldi G, Cianfoni A, Filippiadis D, Scarone P, Bernucci C et al. Intradiscal oxygen-ozone chemonucleolysis versus microdiscectomy for lumbar disc herniation radiculopathy: a non-inferiority randomized control trial. Clinical Study [Internet]. The Spine Journal. 2022; 22(6):895-909 DOI: 10.1016/j.spinee.2021.11.017
8. Borroto Rodríguez V, Abreu Casas D, Rodríguez de la Paz NJ, Prieto Jiménez IL, Álvarez Rosell N. Efectividad de la ozonoterapia en el tratamiento del dolor por hernia de disco intervertebral [Internet]. Rev chil neurocir. 2019 [acceso: 13/08/2023]; 45(1):8-19. Disponible en: https://revistachilenadeneurocirugia.com/index.php/revchilneurocirugia/article/view/4
9. Salmerón Ríos R, Salmerón Ríos S, Tárraga Marcos L, Madrona Marcos F, Tárraga López PJ. Eficacia de la ozonoterapia en el tratamiento de la hernia de disco: Revisión Sistemática [Internet]. JONNPR. 2021; 6(3):588-607. DOI: 10.19230/jonnpr.3874
10. Re K, Gandhi J, Liang R, Patel S, Joshi G, Smith NL, et al. Clinical utility of ozone therapy and hyperbaric oxygen therapy in degenerative disc disease [Internet]. Med Gas Res. 2023; 13(1):1-6. DOI: 10.4103/2045-9912.351890
11. Simon C, Le Corroller T, Pauly V, Creze M, Champsaur P, Guenoun D. Intradiscal oxygen-ozone therapy for the treatment of symptomatic lumbar disc herniation: A preliminary study [Internet]. J Neuroradiol. 2022; 49(2):180-6. DOI: 10.1016/j.neurad.2021.09.004
12. Cruz-Jiménez E, Morejón-Barroso O, Yanes-Isray O, Varela-Castro L, Vilaboy-Pérez B. Efecto terapéutico de la ozonoterapia en pacientes con hernia discal. Centro especializado ambulatorio, Cienfuegos [Internet]. Revista Cubana de Medicina Natural y Tradicional. 2022 [acceso: 07/06/2023]; 4: [aprox. 13 pant.] Disponible en: https://revmnt.sld.cu/index.php/rmnt/article/view/219
13. Cuba Rodríguez LC, Rojas Carmenaty S, Castellanos BY, Cardosa Valladares Y. Ozonoterapia paravertebral en la patología de la columna vertebral lumbar [Internet]. Rev inf cient. 2019 [acceso: 13/04/2023]; 98(3):364-73. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1028-99332019000300364&lng=es
14. Crisol Deza DA, Medeiros Bascope ML. Uso de la ozonoterapia como tratamiento complementario [Internet]. Rev Cuba Reumatol. 2021 [acceso: 07/06/2023]; 23(3):245. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1817-59962021000300002&lng=es
15. Márquez Camayd E, Márquez Torres C, Márquez Torres C, Cruz Aldana Y. Presentación de una paciente portadora tres hernias discales lumbares tratadas con ozono [Internet]. CCM. 2017 [acceso: 14/04/2023]; 21(1):305-10. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1560-43812017000100027&lng=es
16. Bonetti M, Lauritano D, Ottaviani GM, Fontana A, Zambello A, Della Gatta L, et al. Oxygen-Ozone Therapy Associated with Alpha Lipoic Acid Plus Palmitoylethanolamide and Myrrh versus Ozone Therapy in the Combined Treatment of Sciatic Pain Due to Herniated Discs: Observational Study on 318 Patients [Internet]. Int J Environ Res Public Health. 2022; 19(9):5716. DOI: 10.3390/ijerph19095716
17. Schwartz A, Sánchez Martínez G, Sabbah F, Hernández Avilés M. Declaración de Madrid sobre la Ozonoterapia. 3 ed. Madrid: International Scientific Committee of Ozone Therapy; 2020.
18. Calzada-Borroto Y, Borroto-Rodríguez V, Hernández-Díaz B, Beath-Rodríguez R, Díaz-Valdés Y. Ozonoterapia en el dolor crónico ostiomioarticular [Internet]. Revista Cubana de Reumatología. 2023 [acceso: 13/04/2023]; 25(1): [aprox. 7 pant.]. Disponible en: https://revreumatologia.sld.cu/index.php/reumatologia/article/view/1130
19. Borroto Rodríguez V, Abreu Casas D, Rodríguez de la Paz NJ, Prieto Jiménez I, Álvarez Rosell N. Estudio económico de la aplicación de Ozonoterapia en la atención del dolor por hernia de disco intervertebral [Internet]. Rev Chil Neurocirugía. 2019 [acceso: 14/04/2023]; 45(2):113-21. Disponible en: https://revistachilenadeneurocirugia.com/index.php/revchilneurocirugia/article/view/122
20. Martínez Pizarro S. Ozonoterapia para reducir el dolor lumbar [Internet]. Rev Andal Med Deporte. 2020 [acceso: 14/04/2023]; 13(1):3-4. Disponible en: https://ws208.juntadeandalucia.es/ojs/index.php/ramd/article/view/716/1035
Published
2024-05-03
How to Cite
1.
Robert Pozo LM, Figueredo Acosta H. Effectiveness of peridural and paravertebral ozone therapy in the treatment of lumbar discs herniations. Rev Cubana Med Milit [Internet]. 2024 May 3 [cited 2025 Mar. 14];53(2):e024022283. Available from: https://revmedmilitar.sld.cu/index.php/mil/article/view/22283
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