Lymphoma in patients with rheumatic disease and recurrent COVID-19

Authors

Keywords:

rheumatoid arthritis, COVID-19, rheumatic disease, Hodgkin lymphoma, non-Hodgkin lymphoma, Sjogren's syndrome.

Abstract

Introduction: Rheumatic diseases and lymphomas have as common elements the affectation of the immune system, specifically T and B lymphocytes and the presence of viral infections as a possible triggering factor for these diseases. The presence of rheumatic diseases increases the risk of appearance of lymphomas. COVID-19 is a viral disease that affects the immune system, so it could be the trigger for the appearance of lymphomas in patients with rheumatic diseases.
Objective: To present the clinical, epidemiological and laboratory characteristics of 2 patients with rheumatic disease, a history of involvement by COVID-19 on 3 occasions and clinical manifestations of lymphoma.
Clinical case: 2 patients diagnosed with rheumatic diseases and SARS-CoV-2 infection 3 times each are presented. One year after the last respiratory episode, they began with clinical manifestations that allowed for the diagnosis of Hodgkin lymphoma in a 27-year-old male patient with rheumatoid arthritis and non-Hodgkin lymphoma, and a 58-year-old female patient with a history of rheumatoid arthritis and Sjögren's syndrome.
Conclusions: COVID-19 infection may have favored the appearance of lymphomas in patients with rheumatic disease. However, more studies and evidence are needed to confirm this finding.

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Author Biographies

Urbano Solis Cartas, Universidad Nacional de Chimborazo Escuela Superior Politécnica de Chimborazo Hospital Andino de Chimborazo

Especailaista en Reumatologìa

Jorge Luis Valdés González, Escuela Superior Politècnica de Chimborazo

Especialista en Dermatologìa

Wilmar Hernández Perdomo, Universidad de las Amèricas

Ingeniero electrònico

Washington Patricio Vásconez Andrade, Universidad Nacional de Chimborazo

Doctor en Medicina

References

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Published

2023-06-20

How to Cite

1.
Solis Cartas U, Valdés González JL, Hernández Perdomo W, Vásconez Andrade WP. Lymphoma in patients with rheumatic disease and recurrent COVID-19. Rev Cubana Med Milit [Internet]. 2023 Jun. 20 [cited 2025 May 9];52(3):e023022606. Available from: https://revmedmilitar.sld.cu/index.php/mil/article/view/2606

Issue

Vol. 52 No. 3 (2023): July - september

Section

Case Presentation

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