Salivary biomarkers and their usefulness in the early detection of oral cancer
Keywords:
biomarkers, neoplasms of the mouth, saliva, tumor biomarkers.Abstract
Introduction: Head and neck cancer is the sixth most common form of human cancer; It is a challenge for Dentistry to reduce mortality and morbidity due to its cause through the development of diagnostic tools that detect it in its early stages.Objective: To describe the role of salivary biomarkers as a diagnostic tool for the early detection of oral cancer.
Development: Salivary biomarkers provide additional information to that obtained in the histopathological study of this type of cancer and can constitute a non-invasive and low-cost analysis tool for early diagnosis.
Conclusions: Although to date there is no ideal biomarker for the early diagnosis of oral cancer, researchers declare a promising future in the use of saliva as a source of biomarkers for these diseases, due in large part to the direct contact of saliva with the oral mucosa and technological advances in the field of molecular medicine.
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