Solitary pulmonary nodule as a form of presentation of a benign metastasizing leiomyoma
Keywords:
histology, immunohistochemistry, leiomyoma, lung, pulmonary lobectomy.Abstract
Introduction: Leiomyoma is a benign smooth muscle tumor that can occur in different locations; the most common is in the uterus. Lung location is very rare, and they are usually secondary to a primary tumor mainly located in the uterus. Their clinical picture varies from asymptomatic and incidental findings by imaging; even those with the most varied symptoms. They are usually bilateral and multiple, rarely presenting as single solid masses.Objective: To present a clinical case of a solitary pulmonary nodule as a presentation of a pulmonary leiomyoma.
Clinical case: A 51-year-old female patient with a gynecological-obstetric history of a hysterectomy 8 years ago, who presented due to shortness of breath and chest pain. An imaging study revealed a unilateral solid mass in the right lung. Surgical intervention, type upper right pulmonary lobectomy, was decided. The histological study raised the diagnosis of a benign metastatic pulmonary leiomyoma, which was corroborated with immunohistochemical markers.
Conclusions: Pulmonary leiomyoma is a rare clinical entity and constitutes a clinical, histological and imaging challenge.
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References
1. Steiner PE. Metastasizing fibroleiomyoma of the uterus: Report of a case and review of the literature [Internet]. Am J Pathol. 1939 [acceso: 04/08/2023]; 15(1):89-110. Disponible en: https://pubmed.ncbi.nlm.nih.gov/19970436/
2. Zapata González RA, Díaz Quintero CA, Cardona Palacio A, Murillo Echeverri V. Leiomioma pulmonar primario [Internet]. Rev Colomb Cir. 2020 [acceso: 04/08/2023]; 35(4): 659-64. Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S2011-75822020000400659&lng=en
3. Dossegger JM, Carneiro LH, Souza R, MennaM, Marchiori E. Pulmonary benign metastasizing leiomyoma presenting as small, diffuse nodules [Internet]. J Bras Pneumol. 2019; 45(4):e20180318 DOI: 10.1590/1806-3713/e20180318
4. Alzeer A, Wu R. Benign metastasizing leiomyoma [Internet]. Pathology Outlines.com website. 2023 [acceso: 04/08/2023]. Disponible en: https://www.pathologyoutlines.com/topic/lungtumorb9metastasizingleio.html
5. Mucientes F, Robalino C, Klaassen R, Alarcón E, Chuecas F. Leiomioma benigno metastizante: caso clínico con nodulos pulmonares e histerectomía 4 años antes por leiomiomas uterinos [Internet]. Rev chil obstet ginecol. 2012 [acceso: 04/08/2023] ; 77(4): 296-300. Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75262012000400010&lng=es
6. Wu Y, Fan L, Niu Y, Wu Y, Gao W. Pulmonary benign metastasizing leiomyoma simultaneously diagnosed with uterine leiomyoma at first visit before hysteromyomectomy [Internet]. Transl Cancer Res. 2021 [acceso: 04/08/2023]; 10(1):567-70. Disponible en: https://tcr.amegroups.org/article/view/48214
7. Le Guen P, Poté N, Morer L, Taillé C. Spontaneous Regression of Miliary Pattern after Delivery. Benign Pulmonary Metastasizing Leiomyoma [Internet]. Am J Respir Crit Care Med. 2021; 203(7):906-7. DOI: 10.1164/rccm.202005-1932IM
8. Pacheco-Rodriguez G, Taveira-DaSilva AM, Moss J. Benign Metastasizing Leiomyoma [Internet]. Clin Chest Med. 2016;3 7(3):589-95. DOI: 10.1016/j.ccm.2016.04.019
9. Reyes-Esparza A, Miranda-Castañón F, Amaya-Téllez M, González-García E. Leiomioma metastatizante benigno: reporte de caso [Internet]. Gac Mex Oncol. 2022; 21(Supl):123-7 DOI: 10.24875/j.gamo.22000023
2. Zapata González RA, Díaz Quintero CA, Cardona Palacio A, Murillo Echeverri V. Leiomioma pulmonar primario [Internet]. Rev Colomb Cir. 2020 [acceso: 04/08/2023]; 35(4): 659-64. Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S2011-75822020000400659&lng=en
3. Dossegger JM, Carneiro LH, Souza R, MennaM, Marchiori E. Pulmonary benign metastasizing leiomyoma presenting as small, diffuse nodules [Internet]. J Bras Pneumol. 2019; 45(4):e20180318 DOI: 10.1590/1806-3713/e20180318
4. Alzeer A, Wu R. Benign metastasizing leiomyoma [Internet]. Pathology Outlines.com website. 2023 [acceso: 04/08/2023]. Disponible en: https://www.pathologyoutlines.com/topic/lungtumorb9metastasizingleio.html
5. Mucientes F, Robalino C, Klaassen R, Alarcón E, Chuecas F. Leiomioma benigno metastizante: caso clínico con nodulos pulmonares e histerectomía 4 años antes por leiomiomas uterinos [Internet]. Rev chil obstet ginecol. 2012 [acceso: 04/08/2023] ; 77(4): 296-300. Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75262012000400010&lng=es
6. Wu Y, Fan L, Niu Y, Wu Y, Gao W. Pulmonary benign metastasizing leiomyoma simultaneously diagnosed with uterine leiomyoma at first visit before hysteromyomectomy [Internet]. Transl Cancer Res. 2021 [acceso: 04/08/2023]; 10(1):567-70. Disponible en: https://tcr.amegroups.org/article/view/48214
7. Le Guen P, Poté N, Morer L, Taillé C. Spontaneous Regression of Miliary Pattern after Delivery. Benign Pulmonary Metastasizing Leiomyoma [Internet]. Am J Respir Crit Care Med. 2021; 203(7):906-7. DOI: 10.1164/rccm.202005-1932IM
8. Pacheco-Rodriguez G, Taveira-DaSilva AM, Moss J. Benign Metastasizing Leiomyoma [Internet]. Clin Chest Med. 2016;3 7(3):589-95. DOI: 10.1016/j.ccm.2016.04.019
9. Reyes-Esparza A, Miranda-Castañón F, Amaya-Téllez M, González-García E. Leiomioma metastatizante benigno: reporte de caso [Internet]. Gac Mex Oncol. 2022; 21(Supl):123-7 DOI: 10.24875/j.gamo.22000023
Published
2024-05-28
How to Cite
1.
Marrero Rodríguez S, Almarales Milpt YM. Solitary pulmonary nodule as a form of presentation of a benign metastasizing leiomyoma. Rev Cubana Med Milit [Internet]. 2024 May 28 [cited 2025 Apr. 3];53(2):e024041893. Available from: https://revmedmilitar.sld.cu/index.php/mil/article/view/41893
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