Hypothalamic hamartoma, regarding a case with unusual evolution
Keywords:
gelastic epilepsy, hamartoma, hypothalamic neoplasm, partial epilepsiesAbstract
Introduction: Hypotalamic hamartomas are malformations originating in the tuber cibereum and inferior hypothalamus. They have a wide spectrum in their clinical and electroencephalographic presentation, so their diagnosis and treatment are a challenge.
Objective: Describe the clinical evolution, the results of complementary examination and the response to treatment in a patient whit unusual evolution of hypothalamic hamartoma.
Clinical Case: 43-year-old female patient who presented in early childhood with gelastic seizures, without neurodevelopmental or endocrinological problems. In adolescence, she begins with disconnection seizures and sporadic bilateral tonic-clonic seizures; temporal lobe epilepsy is diagnosed. Learning, behavior and social adaptation remained normal. She continued her university studies with excellent performance, at the age of 36 she was diagnosed with hypothalamic hamartoma. She is currently a successful professional, despite not being controlled with anti-seizure medication. She received a gamma knife session without clinical or imaging changes.
Conclusions: A case of hypothalamic hamartoma with unusual evolution is shown, she presents poor control of gelastic seizures that have evolved into status epilepticus, despite which it has a successful professional performance.
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