Conservative treatment of odontogenic myxoma with extensive maxillary involvement
Keywords:
maxilla, maxillary neoplasms, odontogenic tumorsAbstract
Introduction: Odontogenic myxoma is a rare benign tumor of mesenchymal origin with an aggressive behavior of slow and asymptomatic expansion. The treatment is surgical with various options from conservative to radical surgery.
Objective: To present a case of odontogenic myxoma with extensive maxillary involvement with conservative surgical treatment.
Clinical Case: A 14-year-old mixed-race male patient presented swelling with facial deformity. The tomography revealed a 10 x 10 cm isodense lesion with involvement of the orbital floor. The diagnosis of odontogenic myxoma was anatomopathological. Conservative surgery was performed: enucleation with peripheral osteotomy and extraction of involved teeth. Six months later, a maxillary obturator prosthesis was placed, and at 6 years of follow-up the patient was asymptomatic without tumor recurrence.
Conclusions: Odontogenic myxoma is rare and requires surgical treatment; conservative treatment may be a surgical option which requires long-term periodic monitoring to assess recurrence.
Downloads
References
Osman S, Hamouda GM, Eltohami YI. Clinical Spectrum and Treatment of Odontogenic Myxoma: Analysis of 37 Cases [Internet]. J Maxillofac Oral Surg. 2021. DOI: 10.1007/s12663-020-01497-7
Kokubun K, Yamamoto K, Nakajima K, Akashi Y, Chujo T, Takano M, et al. Frequency of Odontogenic Tumors: A Single Center Study of 1089 Cases in Japan and Literature Review [Internet]. Head Neck Pathol. 2022;16(2):494-502. DOI: 10.1007/s12105-021-01390-w
Chrcanovic BR, Gomez RS. Odontogenic myxoma: An updated analysis of 1,692 cases reported in the literature [Internet]. Oral Diseases. 2019;25(3):676-83. DOI: 10.1111/odi.12875
Díaz-Reverand S, Naval-Gías L, Muñoz-Guerra M, González-García R, Sastre-Pérez J, Rodríguez-Campo FJ. Mixoma odontogénico: presentación de una serie de 4 casos clínicos y revisión de la literatura [Internet]. Revista Española de Cirugía Oral y Maxilofacial. 2018;40(3):120-8. DOI: 10.1016/j.maxilo.2017.03.002
Terauchi M, Marukawa E, Hyodo K, Iwasaki T, Wada A, Harada H, et al. Conservative surgical treatment of odontogenic myxoma with preservation of the inferior alveolar nerve. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology [Internet]. 2022;34(2):156-63. DOI: 10.1016/j.ajoms.2021.08.010
Leite-Lima F, da Cunha JF, Lehman LFC, Baires Campos FE, de Castro WH. Surgical management x recurrence of Odontogenic myxoma: Literature review and case reports [Internet]. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 2019;31(3):153-8. DOI: 10.1016/j.ajoms.2019.03.005
Meleti M, Giovannacci I, Corradi D, Manfredi M, Merigo E, Bonanini M, et al. Odontogenic myxofibroma: a concise review of the literature with emphasis on the surgical approach [Internet]. Med Oral Patol Oral Cir Bucal. 2015;20(1):e1-6. DOI: 10.4317/medoral.19842
Subramaniam SS, Heggie AA, Kumar R, Shand JM. Odontogenic myxoma in the paediatric patient: a review of eight cases [Internet]. Int J Oral Maxillofac Surg. 2016;45(12):1614-7. DOI: 10.1016/j.ijom.2016.07.007
Andrews T, Stilianos E. K, Maillard AAJ. Myxomas of the head and neck [Internet]. American Journal of Otolaryngology. 2000;21(3):184-9. DOI: 10.1016/S0196-0709(00)85022-X
Chrcanovic BR, do Amaral MBF, Marigo H de A, Freire-Maia B. An expanded odontogenic myxoma in maxilla [Internet]. Stomatologija. 2010 [acceso: 20/09/2024];12(4):122-8. Disponible en: https://pubmed.ncbi.nlm.nih.gov/21266837/
Rotenberg BW, Daniel SJ, Nish IA, Ngan BY, Forte V. Myxomatous lesions of the maxilla in children: a case series and review of management [Internet]. Int J Pediatr Otorhinolaryngol. 2004;68(10):1251-6. DOI: 10.1016/j.ijporl.2004.04.022
Garcia Rosa AC, Abdalla Rosa C, da Cruz EZ, Alves FF, de Senna AM. Odontogenic myxoma in childhood [Internet]. Human Pathology Reports. 2023; 32:300707. DOI: 10.1016/j.hpr.2023.300707
Tavakoli M, Williamson R. Odontogenic myxomas: what is the ideal treatment? [Internet]. BMJ Case Rep. 2019;12(5):e228540. DOI: 10.1136/bcr-2018-228540
Conto-Palomino JP, Barria-Angulo H, Cruz JIODL, Huamán HO, Atamari-Anahui N. Tratamiento conservador del fibromixoma odontogénico en mandíbula: reporte de dos casos [Internet]. Rev Cuerpo Med HNAAA. 2023;16(2): e1860. DOI: 10.35434/rcmhnaaa.2023.162.1860
Tavakoli M. Literature Review Comparing the Success of Conservative Treatment and Radical Surgery in Treating Odontogenic Myxomas [Internet]. International Journal of Surgery. 2017;47:S52. DOI: 10.1016/j.ijsu.2017.08.271
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Marly Grisel Céspedes-Herrera, JACKELINE PAOLA CONTO-PALOMINO, Hosting Barria-Angulo, Jhames Iván Oré De La Cruz, Hebert Ochoa Huamán, Noé Atamari-Anahui

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Authors who have publications with this Journal accept the following terms:
- The authors will retain their copyright and guarantee the Journal the right of first publication of their work, which will simultaneously be subject to the Creative Commons Attribution License. The content presented here can be shared, copied and redistributed in any medium or format; Can be adapted, remixed, transformed or created from the material, using the following terms: Attribution (giving appropriate credit to the work, providing a link to the license, and indicating if changes have been made); non-commercial (you cannot use the material for commercial purposes) and share-alike (if you remix, transform or create new material from this work, you can distribute your contribution as long as you use the same license as the original work).
- The authors may adopt other non-exclusive license agreements for the distribution of the published version of the work (for example: depositing it in an institutional electronic archive or publishing it in a monographic volume) as long as the initial publication in this Journal is indicated.
- Authors are allowed and recommended to disseminate their work through the Internet (e.g., in institutional electronic archives or on their website) before and during the submission process, which can produce interesting exchanges and increase citations. of the published work.