Dengue and leptospirosis coinfection in a pregnant woman with acute febrile illness
Keywords:
co-infection, dengue, leptospirosisAbstract
Introduction: Dengue and leptospirosis are common causes of acute febrile illness in patients in developing countries. Co-infection with these entities has a high mortality rate if not suspected early.
Objective: To perform the clinical approach to a pregnant patient with dengue and leptospirosis coinfection.
Clinical Case: This manuscript presents the case of a pregnant patient with an acute febrile illness, which turned out to be a co-infection with dengue and leptospirosis, who presented multiple organ failure during hospitalization. However, the patient recovered due to the timely management of these entities.
Conclusions: Coinfection in pregnant women is rarely described in the literature, but a high level of suspicion should be maintained as symptoms may overlap with other obstetric conditions. Timely diagnosis and management are important to significantly reduce severity and mortality.
Downloads
References
1. Jiménez Ibáñez LC, Hernández Pérez SY, García Padrón OA. Fiebre hemorrágica por dengue durante el embarazo. Reporte de un caso [Internet]. Ginecol y Obstet Mex. 2019; 87(4):257-61. DOI: 10.24245/gom.v87i4.2510
2. Acuña Guillén DJ, Vásquez Palomino A, Novoa RH. Leptospirosis severa en el puerperio: informe de un caso [Internet]. Ginecol y Obstet Mex. 2022; 90(06):543-9. DOI: 10.24245/gom.v90i6.6774
3. Watts DM, Russell KL, Wooster MT, Sharp TW, Morrison AC, Kochel TJ, et al. Etiologies of Acute Undifferentiated Febrile Illnesses in and near Iquitos from 1993 to 1999 in the Amazon River Basin of Peru [Internet]. Am J Trop Med Hyg. 2022; 107(5):1114-28. DOI: 0.4269/ajtmh.22-0259
4. Del Valle Mendoza J, Palomares Reyes C, Carrillo Ng H Tarazona-Castro Y, Kym S, Aguilar-Luis MA, et al. Leptospirosis in febrile patients with suspected diagnosis of dengue fever [Internet]. BMC Res Notes. 2021; 14(1):209. DOI: 10.1186/s13104-021-05627-3
5. Chansamouth V, Thammasack S, Phetsouvanh R, Keoluangkot V, Moore CE, Blacksell SD, et al. The Aetiologies and Impact of Fever in Pregnant Inpatients in Vientiane, Laos [Internet]. PLoS Negl Trop Dis. 2016; 10(4):e0004577. DOI: 10.1371/journal.pntd.0004577
6. Soma-Pillay P, Nelson-Piercy C, Tolppanen H, Mebazaa A. Physiological changes in pregnancy [Internet]. Cardiovasc J Afr. 2016; 27(2):89-94. DOI: 10.5830/CVJA-2016-021
7. Mulik V, Dad N, Buhmaid S. Dengue in pregnancy: Review article [Internet]. Eur J Obstet Gynecol Reprod Biol. 2021; 261:205-10. DOI: 10.1016/j.ejogrb.2021.04.035
8. Tien Dat T, Kotani T, Yamamoto E, Shibata K, Moriyama Y, Tsuda H, et al. Dengue fever during pregnancy [Internet]. Nagoya J Med Sci. 2018; 80(2):241–7. DOI: 10.18999/nagjms.80.2.241
9. Selvarajah S, Ran S, Roberts NW, Nair M. Leptospirosis in pregnancy: A systematic review [Internet]. PLoS Negl Trop Dis. 2021; 15(9):e0009747. DOI: 10.1371/journal.pntd.0009747
10. Wijesinghe A, Gnanapragash N, Ranasinghe G, Ragunathan MK. Fatal co-infection with leptospirosis and dengue in a Sri Lankan male [Internet]. BMC Res Notes. 2015; 8:348. DOI: 10.1186/s13104-015-1321-7
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Bryan Walter Angulo Garcia , Carmen Miluska Silva Lopez , Joseph Alburqueque-Melgarejo, Juan Carlos Roque Quezada , Jamee Guerra Valencia

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Authors who have publications with this Journal accept the following terms:
- The authors will retain their copyright and guarantee the Journal the right of first publication of their work, which will simultaneously be subject to the Creative Commons Attribution License. The content presented here can be shared, copied and redistributed in any medium or format; Can be adapted, remixed, transformed or created from the material, using the following terms: Attribution (giving appropriate credit to the work, providing a link to the license, and indicating if changes have been made); non-commercial (you cannot use the material for commercial purposes) and share-alike (if you remix, transform or create new material from this work, you can distribute your contribution as long as you use the same license as the original work).
- The authors may adopt other non-exclusive license agreements for the distribution of the published version of the work (for example: depositing it in an institutional electronic archive or publishing it in a monographic volume) as long as the initial publication in this Journal is indicated.
- Authors are allowed and recommended to disseminate their work through the Internet (e.g., in institutional electronic archives or on their website) before and during the submission process, which can produce interesting exchanges and increase citations. of the published work.