Upper interincisal gingival enlargement in pediatric age
Keywords:
biopsy, granuloma, gingival hyperplasia, peripheral giant cell granulomaAbstract
Introduction: Peripheral giant cell granuloma is a gingival enlargement or reactive hyperplasia that occurs in the gingiva in response to local irritation or chronic trauma.
Objective: To describe the clinical case of a pediatric patient with aesthetic and functional impairment due to an interincisal peripheral giant cell granuloma.
Clinical Case: A 10-year-old male patient presented with a painless, firm, hypercolored, sessile-based, localized enlargement in the upper central interincisal region. This enlargement appeared after minor trauma weeks earlier. An excisional biopsy confirmed the suspected diagnosis of a pyogenic granuloma, but the condition relapsed significantly. Therefore, it was necessary to perform another excisional biopsy, this time with a periodontal flap due to bone involvement.
Conclusions: Peripheral giant cell granuloma can be very aggressive in children, affecting aesthetics and function, and its removal by periodontal flap reduces the possibility of recurrence.
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1. Ahmed MS, Haggag MA. HAS Carnoy’s solution a role in the management of recurrent peripheral giant cell granuloma? [Internet]. J Stomatol Oral Maxillofac Surg. 2022; 123(1):37-43. DOI: 10.1016/j.jormas.2020.12.011
2. Fligelstone S, Ashworth D. Peripheral giant cell granuloma: A case series and brief review [Internet]. Ann R Coll Surg Engl. 2024; 106(7):649-51. DOI: 10.1308/rcsann.2023.0021
3. Hoarau E, Quilhot P, Baaroun V, Lescaille G, Campana F, Lan R, et al. Oral giant cell tumor or giant cell granuloma: How to know? [Internet]. Heliyón. 2023; 9(3):e14087. DOI: 10.1016/j.heliyon.2023.e14087
4. Sharma N, Rana S, Jetley S. Peripheral giant cell granuloma of maxilla [Internet]. J Indian Soc Periodontol. 2022; 26(1):75-8. DOI: 10.4103/jisp.jisp_624_20
5. Sllamniku Dalipi Z, Krasniqi MS, Kondirolli L. Excision of a Benign Peripheral Giant Cell Granuloma in the Oral Mucosa of the Anterior Mandibular
Teeth with a 975-nm Diode Laser: A Case Report of a 39-Year-Old Woman [Internet]. Am J Case Rep. 2023; 24:e938793. DOI: 10.12659/AJCR.938793
6. Wu YH, Wu YC, Lee YP, Chiang CP. Peripheral giant cell granuloma. Case report [Internet]. J Dent Sci. 2022; 17 (3):1434-6. DOI: 10.1016/j.jds.2022.03.005
7. Akerzoul N, Touré B. Surgical excision of peripheral giant cell granuloma of the maxilla: a case report [Internet]. Pan Afr Med J. 2023; 44:141. DOI: 10.11604/pamj.2023.44.141.34835
8. Hernández Peláez L, Fernández Morán E, García Suárez L, De Lucio Delgado A, Villegas Rubio JA. Experiencia con Denosumab en granuloma central de células gigantes [Internet]. Andes pediatr. 2022 [acceso: 18/11/2024]; 93(2):247-52. Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S2452-60532022000200247&lng=es
9. Bolli E, Schinini G, Romanelli H. Granuloma periférico de células gigantes asociado a un implante. Informe de un caso clínico con seguimiento a 5 años [Internet]. Rev Asoc Odontol Argent. 2020 [acceso: 18/11/2024]; 108(2):68-74. Disponible en: https://pesquisa.bvsalud.org/portal/resource/es./biblio-1121446
10. Muela CD, Díaz MJA, Gómez AH, Hernández MMG. An unusually large peripheral giant cell granuloma: a case report [Internet]. Rev Esp Cirur Oral Maxilofac. 2020; 42(2):87-90. DOI: 10.2098/recorn.2020.1083/2019
11. Cordeiro PGL, Rocha MCS. Aspectos clínicos e cirúrgicos do tratamento do granuloma periférico de células gigantes: relato de caso clínico [Internet]. Research, Society and Development. 2020; 9(10):e566910881. DOI: 10.33448/rsd-v9i10.8881
12. Mirza HH, Zalan AK, Maxood A, Gul A, Memon Z, Sulaiman M. Peripheral Giant Cell Granuloma of Posterior Maxillain a 9-Year Child [Internet]. Journal the College of Physicians and Surgeons Pakistan. 2021; 31(4):457-77. DOI: 10.29771/jcpsp.2021.04.475
13. Charcanovic BR, Gomes CC, Gomez RS. Peripheral giant cell granuloma: a systematic review [Internet]. J Stomatol Oral Maxillofac Surg. 2019 [acceso: 18/12/2024]; 120(5):456-61. Disponible en: https://www.sciencedirect.com/science/article/abs/pii/S2468785519300205
14. Alarcón-Arratia A, Muñoz-Repetto M, Schnettler K, Carolina Ulloa M. Granuloma Periférico de Células Gigantes e Hiperparatiroidismo. Presentación de un Caso [Internet]. Int J Odontostomat. 2019 [acceso: 18/12/2024]; 13 (3):266-70. Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718381X2019000300266&lng=es
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