Experience in the endoscopic treatment of biliary lithiasis in children
Keywords:
cholecystectomy; choledocholithiasis; endoscopic retrograde cholangiopancreatography; ERCP; pediatrics; sphincterotomyAbstract
Introduction: Endoscopic retrograde cholangiopancreatography (ERCP) is a useful endoscopic procedure in the treatment of biliary tract stones.
Objective: To describe the level of competence and performance achieved in the endoscopic treatment of biliary stones in children.
Methods: The outcomes were evaluated in a series of 45 pediatric patients with biliary stones who underwent ERCP and laparoscopic cholecystectomy. The competence and performance of the specialists were assessed based on the results in the series and on international standards. Age, sex, reasons for the ERCP indication, type of ERCP, diagnoses made, and procedures performed during the ERCPs were studied.
Results: The mean age was 15 years (range 4–18 years); 33 (73%) were female and 12 (27%) were male. Thirty-four patients (76%) were diagnosed with obstructive jaundice, nine (20%) with symptomatic gallstones underwent laparoscopic cholecystectomy, and two (4%) presented with biliary pancreatitis. Forty-two therapeutic ERCPs (93%) were performed; biliary sphincterotomy and stone extraction were performed in 33 patients (79%). The cannulation rate, gallstone extraction rate, and obstructed duct drainage rate were all 100%. Complications occurred in two patients (4.4%), both minor post-sphincterotomy hemorrhages. There were no deaths. The level of performance was adequate.
Conclusions: The team demonstrated an adequate level of competence and performance in the endoscopic treatment of gallstones in children.
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References
1. Parra-Landazury NM, Cordova-Gallardo J, Méndez-Sánchez N. Obesity and Gallstones [Internet]. Visc Med. 2021;37(5):394-402. DOI: https://doi.org/10.1159/000515545
2. Balanescu R, Moga A, Balanescu L, Untaru M, Caragata R, Cimpeanu P. Cholecystectomy in Children: Indications and Timing [Internet]. Children (Basel). 2025;12(8):1052. DOI: https://doi.org/10.3390/children12081052
3. Desmond A, Sleightholm R, De Beritto T. Hyperbilirubinemia and Choledocholithiasis in an Extremely Premature Neonate [Internet]. Pediatr Ann. 2023;52(8):e297-e302. DOI: https://doi.org/10.3928/19382359-20230613-04
4. Destro F, Pierucci UM, Durante E, Caruso AM, Girgenti V, Canonica CPM, et al. Laparoscopic Cholecystectomy in Children: The Experience of Two Centers Focusing on Indications and Timing in the Era of "New Technologies" [Internet]. Children (Basel). 2023;10(11):1771. DOI: https://doi.org/10.3390/children10111771
5. Gong DF, Cheng L. Efficacy and safety of endoscopic retrograde cholangiopancreatography in the treatment of bile duct stones [Internet]. World J Gastrointest Surg. 2025;17(9):109270. DOI: https://doi.org/10.4240/wjgs.v17.i9.109270
6. Suwatthanarak T, Chinswangwatanakul V, Methasate A, Phalanusitthepha C, Tanabe M, Akita K, Akaraviputh T. Surgical strategies for challenging common bile duct stones in the endoscopic era: A comprehensive review of current evidence [Internet]. World J Gastrointest Endosc.2024;16(6):305-317. DOI: https://doi.org/10.4253/wjge.v16.i6.305
7. Ali FS, DaVee T, Bernstam EV, Kao LS, Wandling M, Hussain MR, et al. Cost-effectiveness analysis of optimal diagnostic strategy for patients with symptomatic cholelithiasis with intermediate probability for choledocholithiasis [Internet]. Gastrointest Endosc. 2022;95(2):327-38. DOI: https://doi.org/10.1016/j.gie.2021.08.024
8. Brizuela Quintanilla RA, Ramos Contreras JY, Ruiz Torres JF, Becil Poyato S, García-Menocal Hernández J, Alonso Contino N, et al. Endoscopic Treatment of Biliopancreatic Affections in Children. Experience in Cuba [Internet]. Acta Scientific Gastroenterology. 2018 [acceso: 17/07/2025];1(1):5-8. Disponible en: https://actascientific.com/ASGIS/pdf/ASGIS-01-0003.pdf
9. Weissman S, Aziz M, Baniqued MR, Taneja V, El-Dallal M, Lee-Smith W, et al. Quality measures in endoscopy: A systematic analysis of the overall scientific level of evidence and conflicts of interest [Internet]. Endosc Int Open. 2022; 10(6):776-86. DOI: https://doi.org/10.1055/a-1809-4219
10. Tintara S, Shah I, Yakah W, Ahmed A, Sorrento CS, Kandasamy C, et al. Evaluating the accuracy of American Society for Gastrointestinal Endoscopy guidelines in patients with acute gallstone pancreatitis with choledocholithiasis [Internet]. World J Gastroenterol. 2022;28(16):1692-1704. DOI: https://doi.org/10.3748/wjg.v28.i16.1692
11. Al Blooshi M, Al Zaabi H, Al Harmoodi F, Al Shamsi M. Retained gallstones after laparoscopic cholecystectomy in kids: a systematic review [Internet]. Pediatr Surg Int. 2025;41(1):229. DOI: https://doi.org/10.1007/s00383-025-06113-8
12. Ugurlu ET. Our experiences in 1000 case single-centre endoscopic retrograde cholangiopancreatography [Internet]. J Minim Access Surg. 2023;19(1):85-94. DOI: https://doi.org/10.4103/jmas.jmas_389_21
13. Lei C, Lu T, Yang W, Yang M, Tian H, Song S, et al. Comparison of intraoperative endoscopic retrograde cholangiopancreatography and laparoscopic common bile duct exploration combined with laparoscopic cholecystectomy for treating gallstones and common bile duct stones: a systematic review and meta-analysis [Internet]. Surg Endosc. 2021;35(11):5918-35. DOI: https://doi.org/10.1007/s00464-021-08648-y
14. Lorio E, Moreau C, Michalek JE, Patel S. Expanding the Use of Endoscopic Retrograde Cholangiopancreatography in Pediatrics: A National Database Analysis of Demographics and Complication Rates [Internet]. Gastroenterology Res. 2022;15(6):314-24. DOI: https://doi.org/10.14740/gr1503
15. Farid M, Baz A, Ramadan A, Elhorbity M, Amer A, Arafa A. Two institutes' experience in laparoendoscopic "rendezvous" technique for patients undergoing laparoscopic cholecystectomy for stones in the gallbladder and bile duct: a prospective randomized comparative clinical trial [Internet]. Updates Surg. 2024;76(6):2237-45. DOI: https://doi.org/10.1007/s13304-024-01973-6
16. Romutis S, Slivka A. Pediatric ERCP: leaving no stone unturned [Internet]. Gastrointest Endosc. 2021; 94(2):318-20. DOI: https://doi.org/10.1016/j.gie.2021.03.057
17. Zdanowicz K, Daniluk J, Marek D,Daniluk U. The Etiology of Cholelithiasis in Children and Adolescents [Internet]. A Literature Review. Int. J. Mol. Sci. 2022; 23(21): 13376. DOI: https://doi.org/10.3390/ijms232113376
18. Lia E, Amri K. Cholelithiasis in children: A characteristic study [Internet]. The Medical Journal of Malaysia. 2022 [acceso: 17/07/2025];77(Suppl 1):59-61. Disponible en: https://pubmed.ncbi.nlm.nih.gov/35899891/
19. Diez S, Müller H, Weiss Ch, Schellerer V, Besendörfer M. Cholelithiasis and cholecystitis in children and adolescents: Does this increasing diagnosis require a common guideline for pediatricians and pediatric surgeons? [Internet]. BMC Gastroenterology. 2021; 21(1):1-10. DOI: https://doi.org/10.1186/s12876-021-01772-y
20. Perera KDR, Nawarathne NMM, Samarawickrama VT, Deraniyagala MP, Luxman WGE, Fernandopulle ANR. Endoscopic Retrograde Cholangiopancreatography in Children: Feasibility, Success, and Safety with Standard Adult Endoscopes and Accessories [Internet]. Pediatr Gastroenterol Hepatol Nutr. 2022; 25(5):406-12. DOI: https://doi.org/10.5223/pghn.2022.25.5.406
21. Cabrera Chamorro CC, Pabón Arteaga JS, Caicedo Paredes CA, Cabrera Bravo N, Villamil Giraldo CE, Chávez Betancourt G, et al. Cholelithiasis and associated complications in pediatric patients [Internet]. Cir Pediatr. 2020 [acceso: 17/07/2025]; 33(4):172-176. Disponible en: https://pubmed.ncbi.nlm.nih.gov/33016656/
22. Fishman DS, Barth B, Man-Wai Tsai C, Giefer MJ, Martinez M, Wilsey M, et al. A prospective multicenter analysis from the Pediatric ERCP Database Initiative: predictors of choledocholithiasis at ERCP in pediatric patients [Internet]. Gastrointest Endosc. 2021;94(2):311-17. DOI: https://doi.org/10.1016/j.gie.2021.01.030
23. Sarli L, Costi R, Gobbi S, Iusco D, Sgobba G, Roncoroni L. Scoring system to predict asymptomatic choledocholithiasis before laparoscopic cholecystectomy. A matched case-control study [Internet]. Surg Endosc. 2003; 17(9):1396-403. DOI: https://doi.org/10.1007/s00464-002-9200-4
24. Almeida RQ, Gerardi Filho VA, Dias JLF, Peres MCT, Waisberg J. Laparoscopic cholecystectomy for symptomatic cholelithiasis in children and adolescents: analysis of 50 cases from a single institution[Internet]. Acta Cir Bras. 2024;39:e394124. DOI: https://doi.org/10.1590/acb394124
25. Vaccari S, Minghetti M, Lauro A, Bellini MI, Ussia A, Khouzam S, et al. Destiny for Rendezvous: Is Cholecysto/Choledocholithiasis Better Treated with Dual- or Single-Step Procedures? [Internet]. Dig Dis Sci. 2022;67(4):1116-27. DOI: https://doi.org/10.1007/s10620-022-07450-7
26. Tintara S, Shah I, Yakah W, Ahmed A, Sorrento CS, Kandasamy C, et al. Evaluating the accuracy of American Society for Gastrointestinal Endoscopy guidelines in patients with acute gallstone pancreatitis with choledocholithiasis [Internet]. World J Gastroenterology. 2022; 28(16):1692-1704. DOI: https://doi.org/10.3748/wjg.v28.i16.1692
27. Sun R, Xu X, Zheng Q, Zhan J. Therapeutic Endoscopic Retrograde Cholangiopancreatography for Pediatric Hepato-Pancreato-Biliary Diseases: A Systematic Review and Meta-Analysis [Internet]. Front Pediatr. 2022; 10:915085. DOI: https://doi.org/10.3389/fped.2022.915085
28. Weng M, Wang L, Weng H, Gu J, Wang X. Utility of endoscopic retrograde cholangiopancreatography in infant patients with conservational endoscopy [Internet]. Transl. Pediatr. 2021; 10(10):2506-13. DOI:https://doi.org/10.21037/tp-21-406
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