Characterization of patients with Acute Pancreatitis in the multipurpose intensive care unit
Keywords:
pancreatitis, APACHE II, acute necrotizing, mortality.Abstract
Introduction: Pancreatitis is the inflammation of the exocrine pancreas, as a result of damage to the acinar cells. Its main clinical features are abdominal pain and elevated serum levels of amylase and lipase. The evolution is very variable, from a complete recovery from a first episode, to a debilitating chronic disease, or death.Objectives: To characterize patients admitted to the intensive care unit with a diagnosis of acute pancreatitis and to evaluate them according to severity criteria.
Methods: A descriptive study was carried out in which 46 medical records of patients admitted with a diagnosis of acute pancreatitis in the multipurpose intensive care unit were reviewed, from January 2014 to December 2019. A database was created with the variables age, etiology, complications, lethality and the application of the Ranson, APACHE II and Balthazar-Hill scales, to evaluate severity and prognosis. An analysis of the frequencies of these variables was carried out.
Results: The age with the highest incidence corresponded to groups under 61 years of age, with a predominance of males. The most frequent cause was gallstones and alcoholism, for 43.4 % and 34.7 % respectively. 47.8 % presented the mild form of the disease. The lethality was 21.7 %.
Conclusions: Severe forms of the disease are more frequent; acute renal failure and acute respiratory failure are the most representative complications.
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References
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20. González-Aguilera J, Díaz-Masó R, Cabrera-Lavernia J, Martí--Garcés G. Índices pronósticos en la predicción de la gravedad de la pancreatitis aguda. Revista Cubana de Medicina Intensiva y Emergencias. 2020 [acceso:01/01/2022]; 19(2): [aprox. 17 p.]. Disponible en: http://www.revmie.sld.cu/index.php/mie/article/view/687
21. Burrowes DP, Choi HH, Rodgers SK, Fetzer DT, Kamaya A. Utility of ultrasound in acute pancreatitis. Abdominal radiology (New York). 2020 [acceso: 01/01/2022]; 45(5):1253-64. Disponible en: https://doi.org/10.1007/s00261-019-02364-x
22. Stojanovic M, Svorcan P, Karamarkovic A, Ladjevic N, Jankovic R, Stevanovic P. Mortality predictors of patients suffering of acute pancreatitis and development of intraabdominal hypertension. Turk J Med Sci. 2019 [acceso: 01/01/2022]; 49(2):506-13. Disponible en: https://pubmed.ncbi.nlm.nih.gov/30997789
23. Dhaka N, Samanta J, Kochhar S, Kalra N, Appasani S, Manrai M, et al. Pancreatic fluid collections: What is the ideal imaging technique? World J Gastroenterol. 2015 [acceso: 01/01/2022]; 21(48):13403-10. Disponible en: https://pubmed.ncbi.nlm.nih.gov/26730150
2. Díaz C, Garzón S, Morales CH, Montoya M. Pancreatitis aguda grave: curso clínico, manejo y factores asociados con mortalidad. Rev Colomb Cir. 2012 [acceso: 01/01/2022]; 27(4): 281-9. Disponible en: https://www.revistacirugia.org/index.php/cirugia/article/view/241
3. Torres López AM, Hoyos Duque SI. Acute pancreatitis: Reflections through the history of the Atlanta Consensus. Iatreia. 2014 [acceso: 01/01/2022]; 27(4):449-59. Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0121-07932014000400008&nrm=iso
4. Banks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, et al. Classification of acute pancreatitis-2012: revision of the Atlanta classification and definitions by international consensus. Gut. 2013 [acceso: 01/01/2022]; 62(1):102-11. Disponible en: https://gut.bmj.com/content/gutjnl/62/1/102.full.pdf
5. Mofidi R, Duff MD, Wigmore SJ, Madhavan KK, Garden OJ, Parks RW. Association between early systemic inflammatory response, severity of multiorgan dysfunction and death in acute pancreatitis. Br J Surg. 2006 [acceso: 01/01/2022]; 93(6):738-44p. Disponible en: https://academic.oup.com/bjs/article/93/6/738/6142313
6. Johnson CD, Abu-Hilal M. Persistent organ failure during the first week as a marker of fatal outcome in acute pancreatitis. Gut. 2004 [acceso: 01/01/2022]; 53(9):1340-4. Disponible en: https://gut.bmj.com/content/53/9/1340.long
7. Singh VK, Bollen TL, Wu BU, Repas K, Maurer R, Yu S, et al. An Assessment of the Severity of Interstitial Pancreatitis. Clinical Gastroenterology and Hepatology. 2011 [acceso: 01/01/2022]; 9(12):1098-103. Disponible en: https://www.sciencedirect.com/science/article/pii/S1542356511009141
8. Fonseca Sepúlveda EV, Guerrero-Lozano R. Acute pancreatitis and recurrent acute pancreatitis: an exploration of clinical and etiologic factors and outcomes. Journal de Pediatria. 2019 [acceso: 01/01/2022]; 95(6):713-9. Disponible en: https://www.sciencedirect.com/science/article/pii/S0021755718303024
9. Bharwani N, Patel S, Prabhudesai S, Fotheringham T, Power N. Acute pancreatitis: The role of imaging in diagnosis and management. Clinical Radiology. 2011 [acceso: 01/01/2022]; 66(2):164-75. Disponible en: https://www.sciencedirect.com/science/article/pii/S0009926010003326
10. Kayar Y, Dertli R, Konur S. Clinical outcomes of acute pancreatitis in elderly patients: An experience of single tertiary center. Pancreatology. 2020 [acceso: 01/01/2022]; 20(7):1296-301. Disponible en: https://www.sciencedirect.com/science/article/pii/S142439032030199X
11. Stigliano S, Belisario F, Piciucchi M, Signoretti M, Delle Fave G, Capurso G. Recurrent biliary acute pancreatitis is frequent in a real-world setting. Digestive and Liver Disease. 2018 [acceso: 01/01/2022]; 50(3):277-82. Disponible en: https://www.sciencedirect.com/science/article/pii/S1590865817313282
12. Leppäniemi A, Tolonen M, Tarasconi A, Segovia-Lohse H, Gamberini E, Kirkpatrick AW, et al. 2019 WSES guidelines for the management of severe acute pancreatitis. World Journal of Emergency Surgery. 2019 [acceso: 01/01/2022]; 14(1):27. Disponible en: https://doi.org/10.1186/s13017-019-0247-0
13. Zhou H, Mei X, He X, Lan T, Guo S. Severity stratification and prognostic prediction of patients with acute pancreatitis at early phase: A retrospective study. Medicine (Baltimore). 2019 [acceso: 01/01/2022]; 98(16): e15275. Disponible en: https://pubmed.ncbi.nlm.nih.gov/31008971
14. Mosko JD, Leiman DA, Ketwaroo GA, Gupta N. Development of Quality Measures for Acute Pancreatitis: A Model for Hospital-Based Measures in Gastroenterology. Clinical Gastroenterology and Hepatology. 2020 [acceso: 01/01/2022]; 18(2):272-5. Disponible en: https://www.sciencedirect.com/science/article/pii/S1542356519313217
15. Alfonso Salabert I, Salabert Tortolo I, Alfonso Prince JC, Álvarez Escobar MdC, Torres Álvarez A, Semper González AI. Factores de riesgo para pancreatitis aguda en el Hospital Comandante Faustino Pérez de Matanzas. Rev. Méd. Electr. 2017 [acceso: 01/01/2022]; 39:1259-68p. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1684-18242017000600007&nrm=iso
16. Marín Ríos DF, Águila Meleros OM, Torres Ajá L, Puerto Lorenzo JA. Morbidity and mortality in patients with acute pancreatitis. Cienfuegos, 2014-2015. Medisur. 2019 [acceso: 01/01/2022]; 17(2): 210-20. Disponible en: http://www.medisur.sld.cu/index.php/medisur/article/view/3830
17. Biberci Keskin E, Taşlıdere B, Koçhan K, Gülen B, İnce AT, Şentürk H. Comparison of scoring systems used in acute pancreatitis for predicting major adverse events. Gastroenterologia y Hepatologia. 2020 [acceso:01/01/2022]; 43(4):193-9. Disponible en: https://www.sciencedirect.com/science/article/pii/S021057051930264X
18. Martínez-Hoed J, López-Jara V. Morbimortalidad de necrosectomía pancreática abierta. Acta Méd. Costarric. 2017 [acceso:01/01/2022]; 59(4): 138-45. Disponible en: http://www.scielo.sa.cr/scielo.php?script=sci_arttext&pid=S0001-60022017000400138&lng=en
19. Garg PK, Singh VP. Organ Failure Due to Systemic Injury in Acute Pancreatitis. Gastroenterology. 2019 [acceso:01/01/2022]; 156(7):2008-23.Disponible en: https://pubmed.ncbi.nlm.nih.gov/30768987
20. González-Aguilera J, Díaz-Masó R, Cabrera-Lavernia J, Martí--Garcés G. Índices pronósticos en la predicción de la gravedad de la pancreatitis aguda. Revista Cubana de Medicina Intensiva y Emergencias. 2020 [acceso:01/01/2022]; 19(2): [aprox. 17 p.]. Disponible en: http://www.revmie.sld.cu/index.php/mie/article/view/687
21. Burrowes DP, Choi HH, Rodgers SK, Fetzer DT, Kamaya A. Utility of ultrasound in acute pancreatitis. Abdominal radiology (New York). 2020 [acceso: 01/01/2022]; 45(5):1253-64. Disponible en: https://doi.org/10.1007/s00261-019-02364-x
22. Stojanovic M, Svorcan P, Karamarkovic A, Ladjevic N, Jankovic R, Stevanovic P. Mortality predictors of patients suffering of acute pancreatitis and development of intraabdominal hypertension. Turk J Med Sci. 2019 [acceso: 01/01/2022]; 49(2):506-13. Disponible en: https://pubmed.ncbi.nlm.nih.gov/30997789
23. Dhaka N, Samanta J, Kochhar S, Kalra N, Appasani S, Manrai M, et al. Pancreatic fluid collections: What is the ideal imaging technique? World J Gastroenterol. 2015 [acceso: 01/01/2022]; 21(48):13403-10. Disponible en: https://pubmed.ncbi.nlm.nih.gov/26730150
Published
2022-04-30
How to Cite
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Guillermo MV, Nuñez Martinez JF, Vasquez CM, Denis IB. Characterization of patients with Acute Pancreatitis in the multipurpose intensive care unit. Rev Cubana Med Milit [Internet]. 2022 Apr. 30 [cited 2025 Apr. 19];51(2):e02201782. Available from: https://revmedmilitar.sld.cu/index.php/mil/article/view/1782
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