Evaluation of the hemostatic effect of 25% red mangrove gel in acute hemorrhage

Authors

Keywords:

animals, hemorrhage, hemostasis, hemostatics, rats, Rhizophoraceae.

Abstract

Introduction: In traditional medicine, hemostatic effects are attributed to parts of the red mangrove plant (Rhizophora mangle).
Objective: To evaluate the hemostatic effect of 25% red mangrove gel on acute hemorrhage.
Methods: A study was carried out in an animal model with 5 groups of albino rats; group I (warfarin), II (phytomenadione), III (0.9% sodium chloride), IV (untreated control) and V (25% red mangrove gel). One limb amputation was produced and the bleeding time (in min) and the amount of bleeding (in g) were measured. A mean comparison analysis was performed with the results of the measurements.
Results: For bleeding time, the means and standard deviations were as follows: Group I (3.12 ± 0.35), group II (1.25 ± 0.30), group III (2.94 ± 0.42); group IV (2.10 ± 0.36) and group V (0.71 ± 0.10). For the amount of bleeding, the means and standard deviations were: Group I (2.97 ± 0.20), group II (1.15 ± 0.38), group III (2.36 ± 0.30), group IV (2.90 ± 0.92) and group V (1.16 ± 0.36). For both variables there were statistically significant differences of groups II and V (p< 0.05) with the other groups and none between group II and IV.
Conclusions: The 25% red mangrove gel presents hemostatic effect similar to phytomenadione, according to the duration and amount of bleeding.

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Author Biography

Idelsis Esquivel Moynelo, Hospital Militar Central “Dr. Luís Díaz Soto”. Departamento de Investigaciones Médico Militares. La Habana, Cuba.

Departamento de Investigaciones Médico Militares

Cargo:INVESTIGADOR

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Published

2023-06-05

How to Cite

1.
Esquivel Moynelo I, Pérez Alejo JL, Vizcaino Cesar M, García Simón G, Casanova Orta RM, Medina López R. Evaluation of the hemostatic effect of 25% red mangrove gel in acute hemorrhage. Rev Cubana Med Milit [Internet]. 2023 Jun. 5 [cited 2025 Jan. 8];52(2):e02302283. Available from: https://revmedmilitar.sld.cu/index.php/mil/article/view/2283

Issue

Vol. 52 No. 2 (2023): April - June

Section

Research Article

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