Antibacterial effect of hydroalcoholic extract of Solanum sessiliflorum Dunal (cocona) on Streptococcus mutans

Authors

Keywords:

antibacterial effect, Solanum sessiliflorum Dunal, Streptococcus mutans, chlorhexidine.

Abstract

Introduction: The search for new extracts of plant origin with antibacterial properties to maintain oral health is essential for the optimal performance of military personnel.
Objectives: To evaluate the antibacterial effect of the hydroalcoholic extract of Solanum sessiliflorum Dunal (cocona) on Streptococcus mutans.
Methods: In vitro and comparative experimental study. A preliminary phytochemical assay of the hydroalcoholic extract of Solanum sessiliflorum Dunal was performed. Forty-eight Müller-Hinton agar plates (Merck ®) were used, distributed in 6 groups (n= 8). Group I (distilled water), group II (70% ethanol), group III (0.12% chlorhexidine), group IV (25% Solanum sessiliflorum Dunal), group V (50%Solanum sessiliflorum Dunal) and group VI (75% Solanum sessiliflorum Dunal); the disc diffusion technique described by Bauer and Kirby was used; the strain used was Streptococcus mutans ATCC 25175 and the inhibition halos were measured at 24 hours to determine the antibacterial activity.
Results: Phenolic compounds, anthocyanins, quinones and cardiotonic glycosides were detected in the phytochemical assay. The antibacterial effect of group VI ( Solanum sessiliflorum Dunal 75%) was proven with 19,831 ± 0,0553 mm (99,37%), comparable to that of 0,12% chlorhexidine (group III) 19,956 ± 0,0431 mm (100%) on Streptococcus mutans ATCC 25175.
Conclusions: The 75% hydroalcoholic extract of Solanum sessiliflorum Dunal shows in vitro antibacterial effect on Streptococcus mutans ATCC 25175 strains with values similar to 0,12% chlorhexidine.

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Author Biographies

Héctor Alexander Vílchez Cáceda, Universidad Inca Garcilaso de la Vega

Laboratorio de Investigación y Desarrollo Farmacéutico

Antonella Rosario Olortegui Quispe, Universidad Inca Garcilaso de la Vega

Laboratorio de Investigación y Desarrollo Farmacéutico

Christhian Alexander Alvia Saldarriaga, Universidad María Auxiliadora

Laboratorio de Investigación y Desarrollo Farmacéutico

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Published

2023-01-01

How to Cite

1.
Vílchez Cáceda HA, Olortegui Quispe AR, Alvia Saldarriaga CA. Antibacterial effect of hydroalcoholic extract of Solanum sessiliflorum Dunal (cocona) on Streptococcus mutans. Rev Cubana Med Milit [Internet]. 2023 Jan. 1 [cited 2025 Apr. 2];52(1):e02302340. Available from: https://revmedmilitar.sld.cu/index.php/mil/article/view/2340

Issue

Vol. 52 No. 1 (2023): January - March

Section

Research Article

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