Clinical characterization of patients with multiple sclerosis

Authors

Keywords:

multiple sclerosis, relapsing-remitting multiple sclerosis, disability, motor disorders.

Abstract

Introduction: Multiple sclerosis is a chronic, inflammatory, demyelinating, autoimmune disease of the central nervous system. It is the first cause of non-traumatic disability in young adults, significantly affecting the quality of life, with physical, social and emotional alterations.
Objective: To characterize from the clinical point of view, patients diagnosed with multiple sclerosis.
Method: A descriptive and cross-sectional observational study was carried out in a case series of 40 patients, with variables age, sex, comorbidity, initial symptoms, clinical forms and degree of disability. A frequency analysis was carried out.
Results: Patients aged between 30 and 39 years (57.5%) predominated. Female patients represented 58.8% of the cases studied and 85.5% presented motor manifestations, as initial symptoms of the disease. Motor symptoms were predominant during the onset of the disease. The most frequent clinical form of multiple sclerosis was relapsing-remitting and the degree of minimal disability.
Conclusions: Motor manifestations are the most frequent initial symptoms, as well as the relapsing-remitting clinical form and the minimum degree of disability. The patients are fundamentally female, in the fourth decade of life.

Downloads

Download data is not yet available.

Author Biographies

Roberto Luis Lotti Mesa, Hospital Clínico Quirúrgico Celia Sánchez Manduley

Especialista del Dpto. de Neurología del Hospital Clínico Quirúrgico Celia Sánchez Manduley

Liudmila Gutiérrez Gacel, Policlínico Universitario Ángel Ortiz Vázquez

Ecografista en Dpto. de Medios Diagnósticos del Policlínico Ángel Ortiz Vázquez

Fidel Jesús Moreno-Cubela, Universidad de Ciencias Médicas de Granma

Presidente del GCE UCMGr

References

1. Arteaga-Noriega A, Zapata-Berruecos J, Castro-Álvarez JF, Benjumea-Bedoya D, Segura-Cardona A, González Gómez D. Factores clínicos y radiológicos relacionados con la progresión de la discapacidad en esclerosis múltiple. Rev. Ecuat. Neurol. 2020 [acceso: 03/12/2021]; 29(1):62-71. Disponible en: http://revecuatneurol.com/wp-content/uploads/2020/06/2631-2581-rneuro-29-01-00062.pdf

2. Ropper AH, Samuels MA, Klein JP. Esclerosis múltiple y otras enfermedades inflamatorias. En: Adams y Victor (ed.). Principios de neurología. Colombia: Mcgraw-Hill; 2017. [acceso: 05/12/2020]. Disponible en: http://accessmedicina.mhmedical.com/content.aspx?bookid=1908

3. Bravo-González F, Álvarez-Roldan A. Esclerosis múltiple, pérdida de funcionalidad y género. Gac Sanit. 2019 [acceso: 03/12/2021]; 33(2):1-8. Disponible en: https://www.scielosp.org/article/gs/2019.v33n2/177-184/es/

4. MS International Federation. Atlas of MS. MS International Federation. [acceso: 03/12/2021]. Disponible en: https://www.atlasofms.org

5. Estrada González R. Casos presentados y discutidos en las sesiones de Neuropatología. Revista Cubana de Cirugía. 1965; 4(2):201-24.

6. Cabrera-Gómez J, Manero-Alfert R. Algunas consideraciones sobre esclerosis múltiple en Latinoamérica. Primera estadística presentada en Cuba. Estudio comparativo. Rev Cub Med. 2020 [acceso: 28/01/2023]; 14:(4):[aprox 18 p.]. Disponible en: https://revmedicina.sld.cu/index.php/med/article/view/948

7. Vázquez-Gómez L, Hidalgo-Mesa C, Beltrán-González B, Broche-Pérez Y, Mederos-Herrera A. Efectividad de una estrategia para el seguimiento multidisciplinario de pacientes con esclerosis múltiple. EDUMECENTRO. 2021 [acceso: 29/01/2023]; 13(4):[aprox. 16 p.]. Disponible en: https://revedumecentro.sld.cu/index.php/edumc/article/view/1887

8. Vázquez-Gómez LA, Hidalgo Mesa C, Beltrán González BM, Broche-Pérez Y, Mederos-Herrera AM. Perfil epidemiológico, clínico e imagenológico de la esclerosis múltiple. Medisur. 2021 [acceso: 29/01/2023]; 19(6):948-58. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1727-897X2021000600948&lng=es

9. Fernández Fernández Ó, Saiz Hinarejos A. Enfermedades desmielinizantes del sistema nervioso central. En: Rozman C, Cardellac López F. Farreras-Rozman Medicina Interna. 19ed. España, Barcelona: Elsevier España; 2020. p. 1394-99.

10. Zarranz Imirizalddu JJ. Neurología 6ta ed. España: Elsevier España; 2018.

11. Hernández-Valero E, Cabrera-Gómez JA, Valenzuela C. Características clínicas de la esclerosis múltiple en el Occidente de Cuba. Comparación con otras dos regiones del país. Rev Neurol. 2004 [acceso: 03/12/2021]; 38(9):818-23. Disponible en: https://neurologia.com/articulo/2003331/esp

12. Correa E, Ortiz M, Guillen, Toral AM, Terán E, Ortaneda D, et al. Prevalence of multiple sclerosis in Cuenca, Ecuador. MSJ. 2019 [acceso: 03/12/2021]; 24(2):738-80. Disponible en: https://journals.sagepub.com/doi/full/10.1177/2055217319884952

13. Rojas Huerto E, Alva Díaz C, Montalván Ayala V. Cambios clínicos de la esclerosis múltiple según modificación de los criterios de McDonald. Hospital Almenara, 2001-2015. An Fac Med. 2019 [acceso: 03/12/2021]; 80(1):34-38. Disponible en: https://doi.org/10.15381/anales.v80i1.15867

14. Vázquez-Céspedes J, Fernández-Morales H, Valverde-Espinosa JA, Moraga-López A, Carazo-Céspedes K. Perfil demográfico y clínico de la esclerosis múltiple en Costa Rica: revisión de la casuística nacional a diciembre de 2017. Neurol Arg. 2021 [acceso: 03/12/2021]; 13(2):69-77. Disponible en: https://www.sciencedirect.com/science/article/pii/S1853002821000070

15. Delgado-Cabrera R, Galán-Palma P, Fernández-Mogollón JL. Características clínico-epidemiológicas de pacientes con esclerosis múltiple en dos hospitales de alta complejidad. Rev.CM HNAAA. 2021 [acceso: 03/12/2021]; 14(1):35-39. Disponible en: http://cmhnaa.org.pe/ojs/index.php/rcmhnaaa/article/viev/868

16. Magyari M, Soelberg Sorensen P. Comorbidity in Multiple Sclerosis. Frontiers in Neurology. 2020 [acceso: 03/12/2021]; 11(851):1-9. Disponible en: https://www.frontiersin.org/articles/10.3389/fneur.2020.00851/full

17. Cárdenas-Robledo S, Otero-Romero S, Passarell-Bacardit MA, Carbonell-Mirabent P, Sastre-Garriga J, Montalbán X. et al. Multiple sclerosis is associated with higher comorbidity and health care resource use: A population-based, case-control study in a western Mediterranean region. Eur J.Neurol. 2021 [acceso: 03/12/2021]; 28(12):1-11. Disponible en: https://doi.org/10.1111/ene.15030

18. Cárdenas-Robledo S, Otero-Romero S, Montalbán X, Tintoré M. Prevalencia e impacto de las comorbilidades en pacientes con esclerosis múltiple. Rev Neurol. 2020 [acceso: 01/01/2022]; 71(4):151-8. Disponible en: https://www.neurologia.com/articulo/2020095

19. Vázquez Gómez LA, Hidalgo Mesa C, Broche Pérez Y, Valdés Morales Y, Tejeda Castañeda E. Caracterización epidemiológica, clínica e imagenológica de pacientes con esclerosis múltiple. Medicen Electrón. 2021 [acceso: 06/12/2021]; 25(3):423-46. Disponible en: http://www.medicentro.sld.cu/index.php/medicentro/article/view/3315/2727

20. García-Estévez DA, Fraga-González C, Ramos-Pacho E, López-Díaz LM, Pardo-Parrado M, Prieto JM. Prevalencia de la esclerosis múltiple en la ciudad de Ourense, Galicia, noroeste de la Península Ibérica. Rev Neurol. 2020 [acceso: 01/01/2022]; 71(1):19-25. Disponible en: https://www.neurologia.com/articulo/2019432

Downloads

Published

2023-03-29

How to Cite

1.
Lotti Mesa RL, Gutiérrez Gacel L, Moreno-Cubela FJ. Clinical characterization of patients with multiple sclerosis. Rev Cubana Med Milit [Internet]. 2023 Mar. 29 [cited 2025 Apr. 11];52(2):e02302474. Available from: https://revmedmilitar.sld.cu/index.php/mil/article/view/2474

Issue

Vol. 52 No. 2 (2023): April - June

Section

Brief Communication

License

Authors who have publications with this Journal accept the following terms:

  • The authors will retain their copyright and guarantee the Journal the right of first publication of their work, which will simultaneously be subject to the Creative Commons Attribution License. The content presented here can be shared, copied and redistributed in any medium or format; Can be adapted, remixed, transformed or created from the material, using the following terms: Attribution (giving appropriate credit to the work, providing a link to the license, and indicating if changes have been made); non-commercial (you cannot use the material for commercial purposes) and share-alike (if you remix, transform or create new material from this work, you can distribute your contribution as long as you use the same license as the original work).
  • The authors may adopt other non-exclusive license agreements for the distribution of the published version of the work (for example: depositing it in an institutional electronic archive or publishing it in a monographic volume) as long as the initial publication in this Journal is indicated.
  • Authors are allowed and recommended to disseminate their work through the Internet (e.g., in institutional electronic archives or on their website) before and during the submission process, which can produce interesting exchanges and increase citations. of the published work.