Clinical, humoral and epidemiological characterization of serious and critically ill patients with COVID-19

Authors

Keywords:

COVID-19, SARS-CoV-2, serious patient, critical patient, intensive care unit.

Abstract

Introduction: Researchers warn of people with severe forms of COVID-19. It is notable the report of these patients, the existence of complications favoring life-threatening situations and the hemogasometric differences and in other biochemical parameters.
Objective: To characterize clinical, epidemiological and humoral aspects of patients with COVID-19 during their stay in the intensive care unit.
Methods: A descriptive and cross-sectional study was carried out in 9 patients with COVID-19 admitted to the intensive care unit from March to May 2020. Data were obtained from medical records. The processed information was expressed in absolute frequencies and percentages and the results were reflected in tables and graphs. Among the variables analyzed were: age, sex, clinical status and at discharge of the patients and fatality.
Results: Men predominated (77,8 %), women evolved better (33,3 % serious, no critical). 88,8 % of the patients had at least one associated chronic disease. 33,3 % of the patients were asymptomatic upon admission, severe pneumonia and acute respiratory distress syndrome were the most frequent cause of complication.
Conclusions: Most of the patients were male and all the critics were male; with similar proportions in age groups; with comorbidities the highest percentage, mainly hypertension; on admission they presented cough, fever, dyspnea and decay; all critical patients took 4 days or more to request medical assistance. The reason for admission to the intensive care unit was severe pneumonia/adult respiratory distress syndrome.

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Author Biographies

Jacno Erik Ferrer Castro, Hospital Militar Dr. Joaquín Castillo Duany de santiago de Cuba

Especialista de 1 y 2 grados en Medicina Intensiva y Emergencias, especialista de 1 grado en MGI, Máster en Urgencias Médicas, Profesor Asistente, Jede de la UTI del hospital militar de sntiago de Cuba

Alejandro Infante Beatón

Hospital Militar "Dr. Joaquín Castillo Duany", Santiago de Cuba, Cuba.

References

1. Rodríguez Morales AJ, Sánchez Duque JA, Hernández Botero S, Pérez Díaz CE, Villamil Gómez WE. Preparación y control de la enfermedad por coronavirus 2019 (COVID-19) en América Latina. Rev Acta Méd Peruana. 2020 [acceso 18 /062020]; 37(1):3-7. Disponible en: https://dx.doi.org/10.35663/amp.2020.371.909

2. Contreras Acosta R, Cueto Chaparro M, Zuluaga de León I de J, Rebolledo Maldonado CE, Morales Vergara CJ. Serie de casos de COVID-19: presentaciones atípicas de la enfermedad. Rev. Colomb. Nefrol. 2020 [acceso: 18 /06/2020];7(2):343-53. Disponible en: https://revistanefrologia.org/index.php/rcn/article/view/461

3. Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical Characteristics of 138 Hospitalized Patients with 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA - J Am Med Assoc. 2020 [acceso:18/06/2020]; 323(11):1061-9. Disponible en: https://jamanetwork.com/journals/jama/article-abstract/2761044

4. Grasselli G, Zangrillo A, Zanella A, Antonelli M, Cabrini L, Castelli A, et al. Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy. Jama. 2020 [acceso: 18 /06/ 2020]; 323(16):1574-81. Disponible en: http: https://jamanetwork.com/journals/jama/article-abstract/2764365

5. Iglesias Pertuz S, Aroca Martinez G, Velez Verbel MA, Cadena Osorio A, Cadena Bonfanti A, Lemus Castro J, et al. Reporte de 4 casos COVID-19 hospitalizados en unidad de cuidados intensivos en una institución hospitalaria en Barranquilla, Colombia. Rev Col Nef. 2020 [acceso: 18/06/2020];7(2): [aprox. 25 p.]. Disponible en: https://revistanefrologia.org/index.php/rcn/article/view/420

6. Ferrer Castro JE, Sánchez Hernández E, Poulout Mendoza A, del Río Caballero G, Figueredo Sánchez D. Caracterización clínica y epidemiológica de pacientes confirmados con la COVID-19 en la provincia de Santiago de Cuba. MEDISAN 2020[acceso: 18/06/2020];24(3): [aprox. 12 p.]. Disponible en: https://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029-30192020000300473

7. Caballero López A, Domínguez Perera MA, Pardo Núñez AB, Abdo Cuza AA. Terapia Intensiva. 4ta ed. La Habana: Editorial Ciencias médicas; 2019.

8. Diaz Ballve L. Enfermedad por coronavirus 2019 (COVID-19), aspectos de interés para cuidados críticos: Revisión narrativa. Rev Arg Ter Int. 2020 [acceso: 23/06/2020];:1-11. Disponible en: https://revista.sati.org.ar/index.php/MI/article/view/698

9. Huang C, Wang Y, Li X, Zhao I, Hu Y, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020 [acceso: 23/06/2020];395(10223):497-506. Disponible en: https://www.sciencedirect.com/science/article/pii/S0140673620301835

10. Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. JAMA. 2020[acceso: 23/06/2020];323(13):1239-42. Disponible en: https://jamanetwork.com/journals/jama/article-abstract/2762130

11. Ronco C, Navalesi P, Vincent JL. Coronavirus epidemic: preparing for extracorporeal organ support in intensive care. Lancet Respir Med. 2020[acceso: 23/06/2020]; 8:240-1. Disponible en: https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(20)30060-6/fulltext

12. Yang J, Zheng Y, Gou X, Pu K, Chen Z, Guo Q, et al. Prevalence of comorbidities in the novel Wuhan coronavirus (COVID-19) infection: a systematic review and meta-analysis. Inter J Infect Dis. 2020 [acceso: 04/07/2020];94(2020):2132-9. Disponible en: https://covid-19.conacyt.mx/jspui/bitstream/1000/593/1/100311.pdf

13. Acosta G, Escobar G, Bernaola G, Alfaro J, Taype W, Marcos C, et al. Caracterización de pacientes con COVID-19 grave atendidos en un hospital de referencia nacional del Perú. Rev Peru Med Exp Salud Publica. 2020 [acceso: 25/06/20];37(2):253-8. Disponible en: https://www.scielosp.org/article/rpmesp/2020.v37n2/253-258/es/

14. Lin M, Beliavsky A, Katz K, Powis JE, Williams V, Science M, et al. What can early Canadian experience screening for COVID-19 teach us about how to prepare for a pandemic? Canadian Medical Association Journal. 2020[acceso: 03/07/2020];192(12):314-8. Disponible en: https://www.cmaj.ca/content/192/12/E314?rss=1&utm_source=TrendMD&utm_medium=cpc&utm_-*campaign=CMAJ_TrendMD_1

15. Xu XW, Wu XX, Jiang XG, Xu KJ, Ying LJ, Ma CL, et al. Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: Retrospective case series. The BMJ. 2020[acceso:04/07/2020];368:1-7. Disponible en: https://www.bmj.com/content/368/bmj.m606.full

16. Pung R, Chiew CJ, Young BE, Chen M, Cin S, Clapham HE, et al. Investigation of three clusters of COVID-19 in Singapore: implications for surveillance and response measures. Lancet. 2020[acceso:04/07/2020]; 395:1039. Disponible en: https://www.sciencedirect.com/science/article/pii/S0140673620305286

17. Serra Valdés MA. Infección respiratoria aguda por COVID-19: una amenaza evidente. Rev haban cienc méd. 2020 [acceso: 24/03/2020]; 19(1):1-5. Disponible en: https://www.revhabanera.sld.cu/index.php/rhab/article/view/3171

18. Klok FA, Kruip MJHA, van der Meer NJM, Arbous MS, Kant KM, Kaptein FHJ, et al. Incidence of thrombotic complications in critically ill ICU patients with COVID-19. Thromb Res. 2020 [acceso: 24/06/2020]; 191:147-5. Disponible en: https://www.sciencedirect.com/science/article/pii/S0049384820301201

19. Henry BM, Aggarwal G, Wong J, Benoitet S, Vikse J, Plebanial M, et al. Lactate dehydrogenase levels predict coronavirus disease 2019 (COVID-19) severity and mortality: A pooled analysis. American Journal of Emergency Medicine. 2020 [acceso: 04/07/2020];38(9):1722-26. Disponible en: https://doi.org/10.1016/j.ajem.2020.05.073

20. Martinez-Outschoorn UE, Prisco M, Ertel A, Tsirigos A, Lin Z, Pavlides S, et al. Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast 13 cancer: achieving personalized medicine via Metabolo-Genomics. Cell Cycle. 2011[acceso: 24/06/2020];10(8):1271-86. Disponible en: https://www.tandfonline.com/doi/full/10.4161/cc.10.8.15330

21. Reinoso Fernández W. Evaluación de la oxigenación, ventilación y difusión. En: Caballero López A, Domínguez Perera MA, Pardo Núñez AB, Abdo Cuza AA. Terapia Intensiva. 4ta ed. La Habana: Editorial Ciencias médicas; 2019. Tomo 3. p.249-55.

22. Chen T, Wu D, Chen H, Yan W, Yan D, Chen G, et al. Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study. BMJ. 2020[acceso: 24/06/2020]; 368:m1091. Disponible en: https://www.bmj.com/content/368/bmj.m1091

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Published

2021-05-04

How to Cite

1.
Ferrer Castro JE, Sánchez Hernández E, Aurora Ortiz Villalón R, Pineda Maure Y, Infante Beatón A. Clinical, humoral and epidemiological characterization of serious and critically ill patients with COVID-19. Rev Cubana Med Milit [Internet]. 2021 May 4 [cited 2025 Apr. 1];50(2):e0210862. Available from: https://revmedmilitar.sld.cu/index.php/mil/article/view/862

Issue

Vol. 50 No. 2 (2021): April - June

Section

Brief Communication

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