Complications of COVID-19 patients and its relation with the evolution and lethality
Keywords:
COVID-19, complications, lethality rate.Abstract
Introduction: The infection by the SARS-CoV-2 virus has become a pandemic that has caused a large number of complications, with fatal evolution in many cases.Objective: To identify complications in patients with COVID-19 and their relationship with evolution and fatality.
Methods: An observational, descriptive study was carried out in 74 patients with a confirmed diagnosis of COVID-19, in the period from March to May 2020. Age variables were included (grouped in: less than 18 years, 18 to 60 years and more than 60 years), sex, personal pathological history, complications and status at discharge. The frequencies, percentages and the fatality rate were calculated.
Results: 52.6% of the patients were male; there were no complications in less than 18 years, 15.7% of those between 18 and 60 years had them and 61.5% of those over 60; severe pneumonia was the most frequent with 37.5%. Only 2 patients with complications evolved unfavorably; there were no apparent differences between the presence of a medical history and the appearance of complications.
Conclusions: The number of complications is low and the evolution is favorable, regardless of these and the personal pathological antecedents; the fatality rate was low.
Downloads
Download data is not yet available.
References
1. Organización Mundial de la Salud. Declaración sobre la segunda reunión del Comité de Emergencias del Reglamento Sanitario Internacional acerca del brote del nuevo coronavirus (2019-nCoV). Ginebra: OMS; 2020 [acceso: 10/05/2020]. Disponible en: https://www.who.int/es/news-room/detail/30-01-2020-statement-onthe-second-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-outbreak-of-novelcoronavirus-(2019-ncov)
2. World Health Organization. Coronavirus disease 2019 (COVID-19). Situation report 42. Geneve: WHO; 2020 [acceso: 02/05/2020]. Disponible en: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200302-sitrep-42-covid-19.pdf?sfvrsn=224c1add_2
3. OMC. Debate sobre Declaración de Helsinki. Última modificación de la Declaración de Helsinki, ¿qué beneficios aporta? Rev OMC. 2009 [acceso: 16/02/2021]; (9):29-34. Disponible en: https://www.cgcom.es/files/cgcom/files/RevistaOMC.9.pdf
4. Ministerio de Salud. Análisis Epidemiológico de la Situación Actual de COVID-19 en el Perú, basado en la información de la Vigilancia Epidemiológica y la Investigación de Campo. Lima: Centro Nacional de Epidemiología, Prevención y Control de Enfermedades; 2020 [acceso: 21/06/ 2020]. Disponible en: https://www.dge.gob.pe/portal/docs/tools/coronavirus/analisiscorona-virus080520.pdf
5. Li Q, Guan X, Wu P, Wang X, Zhou L, Trong Y, et al. Early transmission dynamics in Wuhan, china, of novel coronavirus- infected pneumonia. N Engl J Med. 2020 [acceso: 21/06/ 2020]; 382(13):1199-207. Disponible en: https://doi.org/10.1056/NEJMoa2001316
6. Samada Suárez M, Hernández Perera JC. ¿Predomina la mortalidad por la COVID-19 en el sexo masculino? Boletín Científico del Cimeq. 2020 Jun 29[acceso: 21/06/ 2020];1(15): 6-7. Disponible en: https://instituciones.sld.cu/bolcimeq/2020/06/29/predomina-la-mortalidad-por-la-covid-19-en-el-sexo-masculino/
7. Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA 2020 [acceso: 15/05/2020]; 323(11): 1061-69. Disponible en: https://doi.org/10.1001/jama.2020.1585
8. Mehta P, McAuley DF, Brown M, Sanchez E, Tattersall RS, Manson JJ. COVID-19: consider cytokine storm syndromes and immunosuppression. Lancet. 2020 [acceso: 15/05/2020]; 395(10229):1033-4. Disponible en: https://doi.org/10.1016/S0140-6736(20)30628-0
9. Cao J, Tu WJ, Cheng W, Yu L, Liu Y, K Hu, et al. Clinical Features and Short-term Outcomes of 102 Patients with Coronavirus Disease 2019 in Wuhan, China. Clin Infect Dis. 2020 [acceso: 20/05/2020]; 71(15):748-55. Disponible en: https://doi.org/10.1093/cid/ciaa243
10. Lodigiani C, Iapichino G, Carenzo L, Cecconi M, Ferrazzi P, Sebastian T, et al. Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy. Thromb Res. 2020 [acceso: 20/05/2020]; 191: 9-14. Disponible en: https://dx.doi.org/10.1016/j.thromres.2020.04.024
11. Klok FA, Kruip M, van der Meer N, Arbous MS, Gommers D, Kant KM, et al. Incidence of thrombotic complications in critically ill ICU patients with COVID-19. Thromb Res. 2020 [acceso: 20/05/2020]; 191:145-7. Disponible en: https://doi.org/10.1016/j.thromres.2020.04.013
12. Kuderer NM, Choueiri TK, Shah DP, Shyr Y, Rubinstein SM, Rivera DR, et al. Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study. Lancet. 2020 [acceso: 16/05/2020]; 396(10253):758. DOI: 10.1016/S0140-6736(20)31870-5
13. Pérez Caballero MD, León Álvarez JL, Dueñas Herrera A, Alfonzo Guerra JP, Navarro Despaigne DA, de la Noval García R, et al. Guía cubana de diagnóstico, evaluación y tratamiento de la hipertensión arterial. Rev cubana med. 2017 [acceso: 16/05/2020]; 56(4): 242-321. Disponible en: https://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75232017000400001&lng=es
14. Jain V, Yuan J-M. Systematic review and meta-analysis of predictive symptoms and comorbidities for severe COVID- 19 infection. medRxiv. 2020 [acceso: 20/06/2020]. Preprint. Disponible en: https://doi.org/10.1101/2020.03.15.20035360
15. Wang TJ, Gona P, Larson MG, Levy D, Benjamín EJ, Tofler GH, et al. Multiple biomarkers and the risk of incident hypertension Hypertension. 2007 [acceso:17/06/2020]; 49(3):432-8. DOI: 10.1161/01.HYP.000025695-6.61872.aa
2. World Health Organization. Coronavirus disease 2019 (COVID-19). Situation report 42. Geneve: WHO; 2020 [acceso: 02/05/2020]. Disponible en: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200302-sitrep-42-covid-19.pdf?sfvrsn=224c1add_2
3. OMC. Debate sobre Declaración de Helsinki. Última modificación de la Declaración de Helsinki, ¿qué beneficios aporta? Rev OMC. 2009 [acceso: 16/02/2021]; (9):29-34. Disponible en: https://www.cgcom.es/files/cgcom/files/RevistaOMC.9.pdf
4. Ministerio de Salud. Análisis Epidemiológico de la Situación Actual de COVID-19 en el Perú, basado en la información de la Vigilancia Epidemiológica y la Investigación de Campo. Lima: Centro Nacional de Epidemiología, Prevención y Control de Enfermedades; 2020 [acceso: 21/06/ 2020]. Disponible en: https://www.dge.gob.pe/portal/docs/tools/coronavirus/analisiscorona-virus080520.pdf
5. Li Q, Guan X, Wu P, Wang X, Zhou L, Trong Y, et al. Early transmission dynamics in Wuhan, china, of novel coronavirus- infected pneumonia. N Engl J Med. 2020 [acceso: 21/06/ 2020]; 382(13):1199-207. Disponible en: https://doi.org/10.1056/NEJMoa2001316
6. Samada Suárez M, Hernández Perera JC. ¿Predomina la mortalidad por la COVID-19 en el sexo masculino? Boletín Científico del Cimeq. 2020 Jun 29[acceso: 21/06/ 2020];1(15): 6-7. Disponible en: https://instituciones.sld.cu/bolcimeq/2020/06/29/predomina-la-mortalidad-por-la-covid-19-en-el-sexo-masculino/
7. Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA 2020 [acceso: 15/05/2020]; 323(11): 1061-69. Disponible en: https://doi.org/10.1001/jama.2020.1585
8. Mehta P, McAuley DF, Brown M, Sanchez E, Tattersall RS, Manson JJ. COVID-19: consider cytokine storm syndromes and immunosuppression. Lancet. 2020 [acceso: 15/05/2020]; 395(10229):1033-4. Disponible en: https://doi.org/10.1016/S0140-6736(20)30628-0
9. Cao J, Tu WJ, Cheng W, Yu L, Liu Y, K Hu, et al. Clinical Features and Short-term Outcomes of 102 Patients with Coronavirus Disease 2019 in Wuhan, China. Clin Infect Dis. 2020 [acceso: 20/05/2020]; 71(15):748-55. Disponible en: https://doi.org/10.1093/cid/ciaa243
10. Lodigiani C, Iapichino G, Carenzo L, Cecconi M, Ferrazzi P, Sebastian T, et al. Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy. Thromb Res. 2020 [acceso: 20/05/2020]; 191: 9-14. Disponible en: https://dx.doi.org/10.1016/j.thromres.2020.04.024
11. Klok FA, Kruip M, van der Meer N, Arbous MS, Gommers D, Kant KM, et al. Incidence of thrombotic complications in critically ill ICU patients with COVID-19. Thromb Res. 2020 [acceso: 20/05/2020]; 191:145-7. Disponible en: https://doi.org/10.1016/j.thromres.2020.04.013
12. Kuderer NM, Choueiri TK, Shah DP, Shyr Y, Rubinstein SM, Rivera DR, et al. Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study. Lancet. 2020 [acceso: 16/05/2020]; 396(10253):758. DOI: 10.1016/S0140-6736(20)31870-5
13. Pérez Caballero MD, León Álvarez JL, Dueñas Herrera A, Alfonzo Guerra JP, Navarro Despaigne DA, de la Noval García R, et al. Guía cubana de diagnóstico, evaluación y tratamiento de la hipertensión arterial. Rev cubana med. 2017 [acceso: 16/05/2020]; 56(4): 242-321. Disponible en: https://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75232017000400001&lng=es
14. Jain V, Yuan J-M. Systematic review and meta-analysis of predictive symptoms and comorbidities for severe COVID- 19 infection. medRxiv. 2020 [acceso: 20/06/2020]. Preprint. Disponible en: https://doi.org/10.1101/2020.03.15.20035360
15. Wang TJ, Gona P, Larson MG, Levy D, Benjamín EJ, Tofler GH, et al. Multiple biomarkers and the risk of incident hypertension Hypertension. 2007 [acceso:17/06/2020]; 49(3):432-8. DOI: 10.1161/01.HYP.000025695-6.61872.aa
Published
2021-05-22
How to Cite
1.
Guzmán Pérez N, Oliva Corujo L, Ferrer Castro JE, Serra Rodríguez J. Complications of COVID-19 patients and its relation with the evolution and lethality. Rev Cubana Med Milit [Internet]. 2021 May 22 [cited 2025 Feb. 20];50(2):e0210930. Available from: https://revmedmilitar.sld.cu/index.php/mil/article/view/930
Issue
Section
Brief Communication
License
Authors who have publications with this Journal accept the following terms:
- The authors will retain their copyright and guarantee the Journal the right of first publication of their work, which will simultaneously be subject to the Creative Commons Attribution License. The content presented here can be shared, copied and redistributed in any medium or format; Can be adapted, remixed, transformed or created from the material, using the following terms: Attribution (giving appropriate credit to the work, providing a link to the license, and indicating if changes have been made); non-commercial (you cannot use the material for commercial purposes) and share-alike (if you remix, transform or create new material from this work, you can distribute your contribution as long as you use the same license as the original work).
- The authors may adopt other non-exclusive license agreements for the distribution of the published version of the work (for example: depositing it in an institutional electronic archive or publishing it in a monographic volume) as long as the initial publication in this Journal is indicated.
- Authors are allowed and recommended to disseminate their work through the Internet (e.g., in institutional electronic archives or on their website) before and during the submission process, which can produce interesting exchanges and increase citations. of the published work.
