Digestive manifestations in hospitalized patients with COVID-19

Authors

Keywords:

SARS-CoV-2, COVID-19, digestive symptoms, coronavirus.

Abstract

Introduction: COVID-19 has caused an unprecedented health crisis, as it is an emerging, unprecedented disease with high transmissibility. New different strains from the original variant of the virus have already been identified, which could mean a change in its clinical presentation patterns.
Objective: To describe the digestive manifestations in patients hospitalized due to COVID-19.
Methods: A descriptive, prospective study was carried out in patients diagnosed with COVID-19, admitted among the months of July and September 2021; 136 patients were studied. Each selected patient had the individual medical record compiled. The variables taken into consideration were sex, age, comorbidities, presence of digestive manifestations and duration of digestive symptoms. The average and standard deviation for the duration of the digestive symptoms were calculated, and in the remaining variables, the results were expressed in absolute frequency and percentages.
Results: Digestive manifestations were present in 58,8 % of the patients. Diarrhea occurred in 29,4 %, a with an average duration of approximately 1,9 days, and was the earliest digestive symptom of all those identified. Nausea and anorexia occurred in 25 %; anorexia was the symptom that lasted the longest, with a maximum of 10 days.
Conclusions: The digestive manifestations in hospitalized patients with COVID-19 were diarrhea, nausea, vomiting, epigastric pain, anorexia and dyspepsia, of which the most frequent presentation was: diarrhea, nausea and anorexia.

Downloads

Download data is not yet available.

Author Biographies

Cesar Abrahan Aguero Figueredo, Universidad de Ciencias Médicas de Holguin.Hospital Clínico Quirúrgico" Lucía Iñigiez

Gastroenterólogo. Profesor Asistente

Moyra Agüero Figueredo, Universidad de Ciencias Médicas de Ciego de Ávila.

Especialista en Medicina General Integral. Instructor

Yenier López Barrero, Universidad de Granma

Licenciado en Idioma inglés. Profesor Auxiliar Máster en Ciencias de la Educación

Lilian Zúñiga Fernández, Universidad de Ciencias Médicas de Holguin. Hospital Clínico-Quirurgico Lucía Iñigiez

Gastroenteróloga.Profesora Asistente

References

1. Pelaéz Sánchez O, Bermejo P. Brotes, Epidemias, eventos y otros términos epidemiológicos de uso cotidiano. Rev Cubana Salud Pública. 2020 [acceso: 05/05/2020]; 46(2): 123-32. Disponible en: http://www.revsaludpublica.sld.cu/index.php/spu/article/view/2358

2. Serra Valdés M. COVID-19. De la patogenia a la elevada mortalidad en el adulto mayor y con comorbilidades. Rev haban cienc méd. 2020 [acceso: 20/07/2020]; 19(3): e3379. Disponible en: http://www.revhabanera.sld.cu/index.php/rhab/article/view/3379

3. Góngora Gómez O, Gámez Leyva LR. Manifestaciones extrapulmonares de la infección por el nuevo Coronavirus SARS-CoV-2. Rev haban cienc méd. 2020 [acceso: 20/07/2020]; 19(Supl.): e3378. Disponible en: http://www.revhabanera.sld.cu/index.php/rhab/article/view/3378

4. Jaramillo MD, Jaramillo Trujillo G, Barreto J, Pérez MD, Pérez JS. Covid-19: herramientas de prevención actual en las unidades de endoscopia. Repert. Med. Cir. 2020 [acceso: 20/07/2020]; 29(Supl.1): 15-21. Disponible en: http://10.31260/RepertMedCir.01217372.1046

5. Torres Mesa P. Endoscopia digestiva en tiempos de COVID-19: Resumen de recomendaciones. Rev Colomb Cir. 2020; 35(2): 209-15. DOI:10.30944/20117582.622

6. Garrido Tapia EJ, Manso López AM, Ángeles Salermo M, Ramírez Ramírez G, Rosa Pérez Rodríguez V. Características clínico-epidemiológicas y algunas reflexiones sobre la COVID-19 en Holguín. CCM. 2020 [acceso: 02/09/2021]: 24(3): 839-55. Disponible en: http://recocmed.sld.cu/index.php/cocmed/article/view/3717

7. Góngora-Parra KB, Rodríguez-González N, Serrano-Batista OR. Mimetismo molecular e interacciones entre la glicoproteína S de SARS-CoV-2 y proteínas humanas. Rev Electrónica Dr. Zoilo E. Marinello Vidaurreta. 2021 [acceso: 02/09/2021]: 46(4). 23-38. Disponible en: http://revzoilomarinello.sld.cu/index.php/zmv/article/view/2810

8. Otero W, Martín Gómez M, Ruiz O, Marulanda H. Procedimientos endoscópicos y pandemia COVID-19 Consideraciones básicas. Rev Colomb Gastroenterol. 2020; 35(1): 66-75. : DOI:10.22516/25007440.526

9. Samada Suárez M., Valenzuela Aguilera K. ¿Los síntomas gastrointestinales pueden ser el debut de la COVID-19? Boletín científico del CIMEQ. Actualización médica del SARS‐COV‐2. 2020 [acceso: 22/07/2020]; 8(1): [aprox. 3 p.]. Disponible en: https://doi.org/10.1053/j.gastro.2020.03.065

10. Schlmulson M, Dávalos MF, Berumen J. Alerta: los síntomas gastrointestinales podrías ser una manifestación de la COVID-19. Rev Mex de Gastro. 2020: 85(3): 282-7. DOI: 10.1016/J.RGMX.2020.04.001

11. Tierraseca MS, Serrano EMB, Hernández TB. Manifestación gastrointestinal exclusiva como forma de presentación de infección por coronavirus (COVID-19). Anales de Pediatría. 2020 [acceso: 27/07/2020]; 28(2): [aprox. 5 p.]. Disponible en: https://doi.org/10.1016/j.anpedi.2020.04.021

12. Fang D, Ma J, Guan J. Manifestations of digestive system in hospitalized patients with novel coronavirus pneumonia in Wuhan, China: a single‐center, descriptive study. Chin J Dig; 2020 [acceso: 24/05/2020]; 40(4): [aprox. 15 p.]. Disponible en: https://pesquisa.bvsalud.org/portal/resource/pt/wpr-871462

13. Cheung KS, Hung IF, Chan PP, Lung K, Tso E, Liu R, et al. Gastrointestinal Manifestations of SARS-CoV-2 Infection and Virus Load in Fecal Samples from the Hong Kong Cohort and Systematic Review and Meta-analysis. Gastroenterology Rev. 2020; 12(3): 2-11. DOI: 10.1053/j.gastro.2020.03.065

14. Jin X, Lian JS, Hu JH. Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms. Gastroenterol Hepatol. 2020 [acceso: 24/05/2020]; 12(3): [aprox. 8 pg.]. Disponible en: http://10.1136/gutjnl-2020-320926

15. Mao R, Liang J, Shen J. Implications of COVID-19 for patients with pre-existing digestive diseases. Lancet Gastroenterol Hepatol. 2020 [acceso: 20/7/2020]:; 5(4): 425-7. Disponible en: http://dx.doi.org/10.1016/S2468-1253(20)30076-5

16. Chen N, Zhou M, Dong X. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan China: a descriptive study. Lancet. 2020 [acceso: 20/07/2020] [acceso 20/7/2020]; 14(1): 507-13. Disponible en: http://dx.doi.org/10.1016/S0140-6736(20)30211-7

17. Velarde Ruiz Velasco J, García Jiménez E, Remes Troche J. Manifestaciones hepáticas y repercusión en el paciente cirrótico de COVID-19. Rev. de Gastroenterología de México. 2020 [acceso: 20/07/2020]; 85(3): 303-11. Disponible en: https://doi.org/10.1016/j.rgmx.2020.05.002

18. Hamming I, Timens W, Bulthuis ML. Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis. J Pathol. 2020 [acceso: 20/07/2020]; 32(4): 631-7. Disponible en: http://dx.doi.org/10.1002/path.1570

19. Plasencia-Urizarri TM, Aguilera-Rodríguez R, Almaguer-Mederos LE. Comorbilidades y gravedad clínica de la COVID-19: revisión sistemática y meta-análisis. Rev haban cienc méd. 2020 [acceso: 02/09/2021]; 19(Supl.1): e3389.35-43. Disponible en: http://www.revhabanera.sld.cu/index.php/rhab/article/view/3389

Downloads

Published

2022-05-28

How to Cite

1.
Aguero Figueredo CA, Agüero Figueredo M, López Barrero Y, Zúñiga Fernández L. Digestive manifestations in hospitalized patients with COVID-19. Rev Cubana Med Milit [Internet]. 2022 May 28 [cited 2025 Apr. 19];51(2):e02201884. Available from: https://revmedmilitar.sld.cu/index.php/mil/article/view/1884

Issue

Vol. 51 No. 2 (2022): April - June

Section

Research Article

License

Authors who have publications with this Journal accept the following terms:

  • The authors will retain their copyright and guarantee the Journal the right of first publication of their work, which will simultaneously be subject to the Creative Commons Attribution License. The content presented here can be shared, copied and redistributed in any medium or format; Can be adapted, remixed, transformed or created from the material, using the following terms: Attribution (giving appropriate credit to the work, providing a link to the license, and indicating if changes have been made); non-commercial (you cannot use the material for commercial purposes) and share-alike (if you remix, transform or create new material from this work, you can distribute your contribution as long as you use the same license as the original work).
  • The authors may adopt other non-exclusive license agreements for the distribution of the published version of the work (for example: depositing it in an institutional electronic archive or publishing it in a monographic volume) as long as the initial publication in this Journal is indicated.
  • Authors are allowed and recommended to disseminate their work through the Internet (e.g., in institutional electronic archives or on their website) before and during the submission process, which can produce interesting exchanges and increase citations. of the published work.